Phospholamban: a tiny protein with a prominent role in the regulation of cardiac relaxation and contractility
Phospholamban (PLN) is a small sarcoplasmic reticulum (SR) protein that in the dephosphorylated state tonically inhibits the SR Ca2+-ATPase (SERCA2a). Different type of evidence to be described, points to PLN as a crucial regulator of basal cardiac Ca2+ cycling, contractility and relaxation and as a...
Guardado en:
| Autores principales: | Mattiazzi, Alicia Ramona, Mundiña-Weilenmann, Cecilia, Vittone, Leticia |
|---|---|
| Formato: | Articulo |
| Lenguaje: | Inglés |
| Publicado: |
2010
|
| Materias: | |
| Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/104650 http://hdl.handle.net/11336/61840 |
| Aporte de: |
Ejemplares similares
-
Role of Ca2+-calmodulin dependent phospholamban phosphorylation on the relaxant effect of β-adrenergic agonists
por: Vittone, Leticia Beatriz, et al.
Publicado: (1993) -
Frequency-dependent acceleration of relaxation in mammalian heart: a property not relying on phospholamban and SERCA2a phosphorylation
por: Valverde, Carlos Alfredo, et al.
Publicado: (2005) -
Role of phosphorylation of Thr17 residue of phospholamban in mechanical recovery during hypercapnic acidosis
por: Mundiña-Weilenmann, Cecilia, et al.
Publicado: (2005) -
Role of phospholamban phosphorylation on Thr17 in cardiac physiological and pathological conditions
por: Mattiazzi, Alicia Ramona, et al.
Publicado: (2005) -
Mechanisms involved in the acidosis enhancement of the isoproterenol-induced phosphorylation of phospholamban in the intact heart
por: Vittone, Leticia Beatriz, et al.
Publicado: (1998)