Na<SUP>+</SUP> channel regulation by Ca<SUP>2+</SUP>/calmodulin and Ca <SUP>2+</SUP>/calmodulin-dependent protein kinase II in guinea-pig ventricular myocytes

Aims Calmodulin (CaM) regulates Na+ channel gating through binding to an IQ-like motif in the C-terminus. Ca2+/CaM-dependent protein kinase II (CaMKII) regulates Ca2+ handling, and chronic overactivity of CaMKII is associated with left ventricular hypertrophy and dysfunction and lethal arrhythmias....

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Detalles Bibliográficos
Autores principales:	Aiba, Takeshi, Hesketh, Geoffrey G., Liu, Ting, Carlisle, Rachael, Villa Abrille, María Celeste, O'Rourke, Brian, Akar, Fadi G., Tomaselli, Gordon F.
Formato:	Articulo
Lenguaje:	Inglés
Publicado:	2010
Materias:	Ciencias Médicas Ca2+/cam-dependent protein kinase ii Calcium Calmodulin Na-channel
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/104334 http://hdl.handle.net/11336/61762
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

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