Effects of Chirality on the Antifungal Potency of Methylated Succinimides Obtained by Aspergillus fumigatus Biotransformations. Comparison with Racemic Ones

Eighteen (3R) and (3R,4R)-N-phenyl-, N-phenylalkyl and N-arylsuccinimides were prepared with high enantioselectivity by biotransformation of maleimides with A. fumigatus. This environmentally friendly, clean and economical procedure was performed by the whole-cell fungal bioconversion methodology. T...

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Detalles Bibliográficos
Autores principales:	Sortino, Maximiliano, Postigo, Agustina, Zacchino, Susana
Formato:	article artículo publishedVersion
Lenguaje:	Inglés
Publicado:	MDPI Open Access Publishing 2013
Materias:	biotransformation Aspergillus fumigatus enantioselective reduction enhanced antifungal activity chiral succinimides methylated succinimides
Acceso en línea:	http://hdl.handle.net/2133/2583 http://hdl.handle.net/2133/2583
Aporte de:	Repositorio Hipermedial de la Universidad Nacional de Rosario (UNR) de Universidad Nacional de Rosario

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