A study of the heat-mediated phase transformations of praziquantel hydrates. Evaluation of their impact on the dissolution rate

Comprehensive knowledge of the critical properties of the active pharmaceutical ingredients is a requirement within the modern concept of quality. Praziquantel hemihydrate (HH) and monohydrate (MH) are new solid forms of this antihelmintic agent, which have better solubility properties than the co...

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Autores principales: Salazar Rojas, Duvernis, Kaufman, Teodoro Saúl, Maggio, Rubén Mariano
Formato: article artículo publishedVersion
Lenguaje:Inglés
Publicado: Elsevier 2022
Materias:
Chemometrics
Hot-stage-MIR
Hydrates
Polymorphism
Praziquantel
Acceso en línea:http://hdl.handle.net/2133/25041
http://hdl.handle.net/2133/25041
Aporte de:
Repositorio Hipermedial de la Universidad Nacional de Rosario (UNR) de Universidad Nacional de Rosario

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