Synthesis, Structural Characterization, and In Vitro and In Silico Antifungal Evaluation of Azo-Azomethine Pyrazoles (PhN2(PhOH)CHN(C3N2(CH3)3)PhR, R = H or NO2)

The azo-azomethine imines, R1-N=N-R2-CH=N-R3, are a class of active pharmacological ligands that have been prominent antifungal, antibacterial, and antitumor agents. In this study, four new azo-azomethines, R1 = Ph, R2 = phenol, and R3 = pyrazol-Ph-R’ (R = H or NO2), have been synthesized, structura...

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Detalles Bibliográficos
Autores principales: Fernandez, Dorancelly, Restrepo-Acevedo, Andrés, Rocha-Roa, Cristian, Le Lagadec, Ronan, Abonia, Rodrigo, Zacchino, Susana, Gómez Castaño, Jovanny A., Cuenú-Cabezas, Fernando
Formato: article artículo publishedVersion
Lenguaje:Inglés
Publicado: MDPI 2022
Materias:
Schiff bases
Azomethine compounds
Candida albicans
Cryptococcus neoformans
In silico studies
Molecular docking
QTAIM-C
Acceso en línea:http://hdl.handle.net/2133/23341
http://hdl.handle.net/2133/23341
Aporte de:
Repositorio Hipermedial de la Universidad Nacional de Rosario (UNR) de Universidad Nacional de Rosario

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