Phagocytic and pinocytic uptake of cholesterol in Tetrahymena thermophila impact differently on gene regulation for sterol homeostasis

The ciliate Tetrahymena thermophila can either synthesize tetrahymanol or when available, assimilate and modify sterols from its diet. This metabolic shift is mainly driven by transcriptional regulation of genes for tetrahymanol synthesis (TS) and sterol bioconversion (SB). The mechanistic details o...

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Detalles Bibliográficos
Autores principales: Hernández, Josefina, Gabrielli, Matías, Costa, Joaquín, Uttaro, Antonio Domingo
Lenguaje:Inglés
Publicado: Nature Research 2022
Materias:
Biological Transport
Cholesterol
Gene Expression Regulation
Homeostasis
Tetrahymena Thermophila
Endoplasmic Reticulum
Sterols
Acceso en línea:http://hdl.handle.net/2133/23320
http://hdl.handle.net/2133/23320
Aporte de:
Repositorio Hipermedial de la Universidad Nacional de Rosario (UNR) de Universidad Nacional de Rosario

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