Interhelical H-Bonds Modulate the Activity of a Polytopic Transmembrane Kinase

DesK is a Histidine Kinase that allows Bacillus subtilis to maintain lipid homeostasis in response to changes in the environment. It is located in the membrane, and has five transmembrane helices and a cytoplasmic catalytic domain. The transmembrane region triggers the phosphorylation of the catalyt...

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Autores principales: Almada, Juan Cruz, Bortolotti, Ana, Ruysschaert, Jane Marie, De Mendoza, Diego, Cybulski, Larisa Estefanía
Formato: article artículo publishedVersion
Lenguaje:Inglés
Publicado: MDPI 2022
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Acceso en línea:http://hdl.handle.net/2133/23273
http://hdl.handle.net/2133/23273
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