Optimization and biological validation of an in vitro assay using the transfected Dm28c/pLacZ Trypanosoma cruzi strain
There is an urgent need to develop safer and more effective drugs for Chagas disease, as the current treatment relies on benznidazole (BZ) and nifurtimox (NFX). Using the Trypanosoma cruzi Dm28c strain genetically engineered to express the Escherichia coli b-galactosidase gene, lacZ, we have adapted...
Guardado en:
| Autores principales: | Gulin, Julián Ernesto Nicolás, Rocco, Daniela Marisa, Alonso, Victoria Lucía, Cribb, Pamela, Altcheh, Jaime, García-Bournissen, Facundo |
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| Lenguaje: | Inglés |
| Publicado: |
Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | http://hdl.handle.net/2133/23254 http://hdl.handle.net/2133/23254 |
| Aporte de: |
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