Characterisation of ST25 NDM-1-producing Acinetobacter spp. strains leading the increase in NDM-1 emergence in Argentina

Carbapenem-resistant Acinetobacter baumannii are recognised by the US Centers for Disease Control and Prevention (CDC) as an urgent threat [1]. The most prevalent mechanism of carbapenem resistance in Acinetobacter spp. is due to the presence of carbapenem-hydrolysing class D β-lactamases, with...

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Detalles Bibliográficos
Autores principales: Rodgers, Deja, Pasteran, Fernando, Calderon, Manuel, Jaber, Sara, Traglia, German M., Albornoz, Ezequiel, Corso, Alejandra, Vila, Alejandro J., Bonomo, Robert A., Adams, Mark D., Ramírez, María Soledad
Formato: article artículo publishedVersion
Lenguaje:Inglés
Publicado: Elsevier 2021
Materias:
Acinetobacter baumannii
NDM-1
Argentina
Carbapenems Resistance
Acceso en línea:http://hdl.handle.net/2133/20493
http://hdl.handle.net/2133/20493
Aporte de:
Repositorio Hipermedial de la Universidad Nacional de Rosario (UNR) de Universidad Nacional de Rosario
Descripción
Sumario:Carbapenem-resistant Acinetobacter baumannii are recognised by the US Centers for Disease Control and Prevention (CDC) as an urgent threat [1]. The most prevalent mechanism of carbapenem resistance in Acinetobacter spp. is due to the presence of carbapenem-hydrolysing class D β-lactamases, with OXA-23 being the most common. The observed dispersion of blaOXA-23 is attributed in part to the spread of successful A. baumannii global clones such as GC1 and GC2 [2]. However, in the most recent years an increased emergence of blaNDM-1-harbouring Acinetobacter spp. isolates has been reported

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