Lovastatin enhances the antitumoral and apoptotic activity of doxorubicin in murine tumor models

Despite its effectiveness as an antineoplastic drug, doxorubicin (DOX) is usually associated with cardiotoxicity. Lovastatin (LOV), a hypolipidemic agent used in the clinic, has been demonstrated to have antitumoral and antimetastatic effects in murine models. Since the two agents arrest tumor cells...

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Autores principales:	Rozados, Viviana R., Hinrichsen, Lucila Isabel, Binda, María Mercedes, Gervasoni, Silvia I., Matar, Pablo, Bonfil, Daniel R., Scharovsky, O. Graciela
Formato:	artículo publishedVersion article
Lenguaje:	Inglés
Publicado:	Spandidos (Grecia) 2012
Materias:	Lovastatin Doxorubicin Apoptosis
Acceso en línea:	http://hdl.handle.net/2133/2014 http://hdl.handle.net/2133/2014
Aporte de:	Repositorio Hipermedial de la Universidad Nacional de Rosario (UNR) de Universidad Nacional de Rosario

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