COA6 is structurally tuned to function as a thiol-disulfide oxidoreductase in copper delivery to mitochondrial cytochrome c oxidase

In eukaryotes, cellular respiration is driven by mitochondrial cytochrome c oxidase (CcO), an enzyme complex that requires copper cofactors for its catalytic activity. Insertion of copper into its catalytically active subunits, including COX2, is a complex process that requires metallochaperones a...

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Detalles Bibliográficos
Autores principales:	Soma, Shivatheja, Morgada, Marcos Nicolás, Naik, Mandar T., Boulet, Aren, Roesler, Anna A., Dziuba, Nathaniel, Ghosh, Alok, Yu, Qinhong, Lindahl, Paul A., Ames, James B., Leary, Scot C., Vila, Alejandro J., Gohil, Vishal M.
Formato:	article artículo publishedVersion
Lenguaje:	Inglés
Publicado:	Cell Press 2021
Materias:	Cytochrome c Oxidase Assembly factor 6 (COA6) Cytochrome c Oxidase subunit 2 (COX2) Mitochondria SCO1 Cytochrome c Oxidase Assembly Protein 1 SCO2 Cytochrome c Oxidase Assembly Protein 2 Copper Metallochaperones
Acceso en línea:	http://hdl.handle.net/2133/19986 http://hdl.handle.net/2133/19986
Aporte de:	Repositorio Hipermedial de la Universidad Nacional de Rosario (UNR) de Universidad Nacional de Rosario

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