Adaptive downregulation of Cl- /HCO3 - exchange activity in rat hepatocytes under experimental obstructive cholestasis

In obstructive cholestasis, there is an integral adaptive response aimed to diminish the bile flow and minimize the injury of bile ducts caused by increased intraluminal pressure and harmful levels of bile salts and bilirrubin. Canalicular bicarbonate secretion, driven by the anion exchanger 2 (A...

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Autores principales: Miszczuk, Gisel Sabrina, Banales, Jesus M., Zucchetti, Andrés E., Pisani, Gerardo Bruno, Boaglio, Andrea C., Saez, Elena, Medina, Juan F., Roma, Marcelo Gabriel, Crocenzi, Fernando A.
Formato: article artículo publishedVersion
Lenguaje:Inglés
Publicado: Public Library of Science (PLOS) 2021
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Acceso en línea:http://hdl.handle.net/2133/19973
http://hdl.handle.net/2133/19973
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