NF-κB inhibitors, unique γ-pyranolγ-lactams with sulfde and sulfoxide moieties from Hawaiian plant Lycopodiella cernua derived fungus Paraphaeosphaeria neglecta FT462

LC-UV/MS-based metabolomic analysis of the Hawaiian endophytic fungus Paraphaeosphaeria neglecta FT462 led to the identifcation of four unique mercaptolactated γ-pyranol–γ-lactams, paraphaeosphaerides E–H (1–4) together with one γ-lactone (5) and the methyl ester of compound 2 (11). The structure...

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Autores principales: Li, Chun-shun, Sarotti, Ariel Marcelo, Huang, Peng, Dang, Uyen T., Hurdle, Julian G., Kondratyuk, Tamara P., Pezzuto, John M., Turkson, James, Cao, Shugeng
Formato: article artículo publishedVersion
Lenguaje:Inglés
Publicado: Nature 2021
Materias:
Lycopodiella cernua
Paraphaeosphaeria neglecta
Biologically Active Secondary Metabolites
NF-κB Inhibitors
Acceso en línea:http://hdl.handle.net/2133/19657
http://hdl.handle.net/2133/19657
Aporte de:
Repositorio Hipermedial de la Universidad Nacional de Rosario (UNR) de Universidad Nacional de Rosario

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