Formation of foamy macrophages by tuberculous pleural effusions is triggered by the interleukin-10/Signal transducer and activator of transcription 3 axis through ACAT upregulation

The ability of Mycobacterium tuberculosis (Mtb) to persist in its human host relies on numerous immune evasion strategies, such as the deregulation of the lipid metabolism leading to the formation of foamy macrophages (FM). Yet, the specific host factors leading to the foamy phenotype of Mtb-infecte...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Genoula, Melanie, Marín Franco, José Luis, Dupont, Maeva, Kviatcovsky, Denise, Milillo, Ayelén, Schierloh, Pablo, Moraña, Eduardo Jose, Poggi, Susana, Palmero, Domingo, Mata-Espinosa, Dulce, González-Domínguez, Erika, León Contreras, Juan Carlos, Barrionuevo, Paula, Rearte, Bárbara, Córdoba Moreno, Marlina Olyissa, Fontanals, Adriana, Crotta Asis, Agostina, Gago, Gabriela, Cougoule, Céline, Neyrolles, Olivier, Maridonneau-Parini, Isabelle, Sánchez-Torres, Carmen, Hernández-Pando, Rogelio, Vérollet, Christel, Lugo-Villarino, Geanncarlo, Sasiain, María del Carmen, Balboa, Luciana
Formato: article artículo publishedVersion
Lenguaje:Inglés
Publicado: Frontiers Media 2020
Materias:
ACAT
Interleukin-10
Foamy macrophages
Lipids
Signal transducer and activator of transcription 3
Tuberculosis
Acceso en línea:http://hdl.handle.net/2133/19501
http://hdl.handle.net/2133/19501
Aporte de:
Repositorio Hipermedial de la Universidad Nacional de Rosario (UNR) de Universidad Nacional de Rosario

Ejemplares similares

Ejemplares similares