Solvent-free microwave-assisted synthesis of novel pyrazolo[40 ,30 :5,6]pyrido[2,3-d]pyrimidines with potential antifungal activity

Novel fused pyrazolo[40 ,30 :5,6]pyrido[2,3-d]pyrimidines 5 were prepared by a solvent-free microwave assisted reaction of heterocyclic o-aminonitriles 3 and cyanopyridines 4 in the presence of tBuOK as catalyst. This protocol provides a versatile procedure for the synthesis of the title compou...

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Autores principales: Acosta, Paola, Insuasty, Braulio, Ortiz, Alejandro, Abonia, Rodrigo, Sortino, Maximiliano, Zacchino, Susana, Quiroga, Jairo
Formato: article artículo publishedVersion
Lenguaje:Inglés
Publicado: Elsevier 2020
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Acceso en línea:http://hdl.handle.net/2133/19493
http://hdl.handle.net/2133/19493
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