New therapeutic targets in somatotropinomas: SHP2 and FGFR4

Octreotide (OCT), a somatostatin analog, binds to the SSTR2 receptor, acting as an anti-secretory for GH and exhibiting anti-proliferative effects in somatotropinomas. In this type of tumors, the FGFR4 receptor has been described as a prognostic and therapeutic biomarker. Furthermore, studies sugges...

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Autores principales: García Barberá , F, Picech , F, Sosa , LDV, De Batista , J, Cecenarro , L, Calafat, P, Mukdsi, J, Petiti, JP
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2023
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Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/42829
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