Monodosis de FLEROXACINA para el tratamiento de la diarrea aguda estival en el adulto
Ihe purpose of this worL was lo evaluate Ihe ef113cacv and safi2tv ofa single dose of400 mgofllcroxacin foithe enlpiric antibiotic treat- inent oí' acote diarrhea in adu It patients. A prospective. double-blincl, placebo-control led, randomizcd trial vas designed. Al! the adult patients vho con...
Guardado en:
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Artículo revista |
| Lenguaje: | Español |
| Publicado: |
Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
2023
|
| Materias: | |
| Acceso en línea: | https://revistas.unc.edu.ar/index.php/med/article/view/40385 |
| Aporte de: |
| Sumario: | Ihe purpose of this worL was lo evaluate Ihe ef113cacv and safi2tv ofa single dose of400 mgofllcroxacin foithe enlpiric antibiotic treat- inent oí' acote diarrhea in adu It patients. A prospective. double-blincl, placebo-control led, randomizcd trial vas designed. Al! the adult patients vho consu llecl iii our hospital br acute d iarrhea from December 1994 lo Apri 1 1995 were included. 72 patients were random- ized ni receive a single dose of 11eroxacin400 me and 73 were placebo. 1b rt -eight patients in each group were evaluable for efbcac) Bet\een both groups there were nol siatistical l sigtflcant dil'ferences in age, sex, number oí' ]ose stoo!s pci' clav at inclusion. davs since lile onset of svnlptoms op tu inclusion, other svnlpronis than ciiarrhea lit inclusion, percent- ages of bacterial pathogens and parasites sn- atecl aoci svniplonlatic treatnient indicatecl. At ihe thircl da) since inclusion. clinical cure oc- corred in 72.2% of lile patients receiving tieroxacin. comparecl Nviili 36.4% ofthose ie- ceivinc,p!aceho: p-0.002. Tilo niean±SD time tu cure was 2.2- 1 .2 davs iii the llel'oxacm gi'otip and13 .2—.() cla\s iii the placebo group: p=O.O 1 lwent\ -e¡(—,lit and 16.7% of patients reporteci aciverse et'6cts in lhc ileroxacin aoci placeboeroups respectiveiv: p=0.3. ¡lis concbuded that a singlecloscof lleroxacin 400 mg san effective and sale alternative for the entpiric antibiotic treatineni ob acote diarrhea o adults. |
|---|