Insufficient elevation of TSH before therapy with I131 in a patient with metastatic differentiated thyroid carcinoma

Guidelines suggest a thyrotropin (TSH) stimulation level ≥30 mIU/l for the administration of 131-iodine (I131) in patients with differentiated thyroid carcinoma (DTC). We present a patient with follicular thyroid carcinoma (FTC), with spinal metastasis as the initial manifestation, who after 6 weeks...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Ramírez Stieben, Luis Agustín, Queralt, Mariana, Sylvestre Begnis, Gustavo, Polillo, David, Barrenechea, Ignacio
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2023
Materias:
thyroid neoplasms
thyrotropine
iodine
neoplasias de la tiroides
tirotropina
yodo
neoplasias da glândula tireoide
tireotropina
iodo
Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/38112
Aporte de:
Revista de la Facultad de Ciencias Médicas de Córdoba de Universidad Nacional de Córdoba
Descripción
Sumario:Guidelines suggest a thyrotropin (TSH) stimulation level ≥30 mIU/l for the administration of 131-iodine (I131) in patients with differentiated thyroid carcinoma (DTC). We present a patient with follicular thyroid carcinoma (FTC), with spinal metastasis as the initial manifestation, who after 6 weeks without levothyroxine did not present an elevation of ≥30 mIU/l of TSH. This situation was interpreted as secondary to the presence of functioning metastases and it was decided, regardless of the TSH level, to administer a therapeutic dose of I131, with iodine-uptake lesions in the liver and spine being confirmed.

Ejemplares similares