Fosfatasa alcalina placenta ria de alto peso molecular en plasma de mujeres embarazadas durante el último trimestre de gestación
l-luni an hlood plasma conidios alkal inc phosphatasc (1-:(' 3. 1 .3. 1) isoenzymes from hone, 1 ver and intcstine. B lood of pregnantwomen in the third trimester of gestation also contains afl isoenzynle of alkalinc phosphaiase froni placenta. placental-AP (PLAP). Seruni f'roni pregnint w...
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| Autores principales: | , , |
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| Formato: | Artículo revista |
| Lenguaje: | Español |
| Publicado: |
Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
2001
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| Materias: | |
| Acceso en línea: | https://revistas.unc.edu.ar/index.php/med/article/view/37290 |
| Aporte de: |
| Sumario: | l-luni an hlood plasma conidios alkal inc phosphatasc (1-:(' 3. 1 .3. 1) isoenzymes from hone, 1 ver and intcstine. B lood of pregnantwomen in the third trimester of gestation also contains afl isoenzynle of alkalinc phosphaiase froni placenta. placental-AP (PLAP). Seruni f'roni pregnint women in the last ini mester of gesialion shows activity of soluble placental alkaline phosphatase (sol-PLAP). It is also known thai a membrane bound high molecular wcight placental-AP (high Mi--PLAP) is preseni in butanol extract s 1 rom placental tissue. Neventheless. up to now. high Mi-PLAP has not hecn founded in human plasma. A rnethod developed in this laboratory al lows detection of membrane-hound alkaline phosphatase in pellet of pltsrrii centrtf'uged at 100.000xg. By applyinglii is nieihod wc have detected high molecular weight placental alkaline phosphatasc in plas- ma of healthy pregnani wonien ni the third trinicster of prcgnancy. |
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