Hepatitis associated aplastic anemia during SARS-CoV-2 pandemic

The hepatitis-associated aplastic anemia is one of the acquired bone marrow failure syndromes. It is a stereotyped form of presentation of aplastic anemia and accounts for 2 - 5 % of the cases in the West. Its treatment, which does not differ from that of aplastic anemia, consists of immunosuppressi...

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Autores principales: Santarelli, Ignacio Martín, Manzella, Pedro Oscar, Gasco González, Francisco, Ingold, Julián José, Olivieri, Melissa Alejandra, Cloobs Venezia, Maximiliano Ariel, Fernández, Sofía Isabel, Melero, Marcelo José
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2022
Materias:
anemia, aplastic
hepatitis
coronavirus infections
anemia aplásica
infecciones por coronavirus
anemia aplástica
hepatite
infecções por coronavirus
Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/35138
Aporte de:
Revista de la Facultad de Ciencias Médicas de Córdoba de Universidad Nacional de Córdoba
id I10-R327-article-35138
record_format ojs
spelling I10-R327-article-351382022-08-19T21:47:05Z Hepatitis associated aplastic anemia during SARS-CoV-2 pandemic Anemia aplásica asociada a hepatitis durante la pandemia por SARS-CoV-2 Anemia aplástica associada a hepatite durante a pandemia de SARS-CoV-2 Santarelli, Ignacio Martín Manzella, Pedro Oscar Gasco González, Francisco Ingold, Julián José Olivieri, Melissa Alejandra Cloobs Venezia, Maximiliano Ariel Fernández, Sofía Isabel Melero, Marcelo José anemia, aplastic hepatitis coronavirus infections anemia aplásica hepatitis infecciones por coronavirus anemia aplástica hepatite infecções por coronavirus The hepatitis-associated aplastic anemia is one of the acquired bone marrow failure syndromes. It is a stereotyped form of presentation of aplastic anemia and accounts for 2 - 5 % of the cases in the West. Its treatment, which does not differ from that of aplastic anemia, consists of immunosuppression when bone marrow transplant is not possible. Nonetheless, during the SARS-CoV-2 pandemic, recommendations restricting the use of antithymocyte globulin to those cases with the highest risk of death have been issued, since the prognosis of CoViD-19 tends to be worse if administered. We present an otherwise-healthy 18-year-old male who was diagnosed with a hepatitis-associated aplastic anemia and received a personalized treatment following these recommendations. La anemia aplásica asociada a hepatitis es uno de los síndromes de fallo medular adquirido. Es una forma estereotipada de presentación de la anemia aplásica adquirida y representa el 2 - 5 % de los casos en occidente. Su tratamiento, que no difiere del de la anemia aplásica adquirida, consiste en inmunosupresión cuando el trasplante de células progenitoras hematopoyéticas no es posible. Sin embargo, durante la pandemia por SARS-CoV-2 se han publicado recomendaciones mediante las cuales se restringe el uso de globulina antitimocítica para aquellos casos con riesgo de muerte porque el pronóstico de la CoViD-19 tiende a ser peor con su uso. Presentamos el caso de un varón de 18 años previamente sano a quien se le diagnosticó una anemia aplásica asociada a hepatitis y se le personalizó el tratamiento acorde a estas recomendaciones. A anemia aplástica associada à hepatite é uma das síndromes de insuficiência medular adquirida. É uma forma estereotipada de apresentação da anemia aplástica adquirida e representa 2 a 5% dos casos no Ocidente. Seu tratamento, que não difere da anemia aplástica adquirida, consiste na imunossupressão quando o transplante de células progenitoras hematopoéticas não é possível. No entanto, durante a pandemia de SARS-CoV-2, recomendações foram publicadas restringindo o uso de globulina antitimócito para os casos com risco de morte, pois o prognóstico do CoViD-19 tende a ser pior com seu uso. Apresentamos o caso de um homem de 18 anos, previamente hígido, que foi diagnosticado com anemia aplástica associada a hepatite e o tratamento foi personalizado de acordo com essas recomendações. Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2022-06-06 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Text Texto Texto application/pdf text/html https://revistas.unc.edu.ar/index.php/med/article/view/35138 10.31053/1853.0605.v79.n2.35138 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 79 No. 2 (2022); 201-204 Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 79 Núm. 2 (2022); 201-204 Revista da Faculdade de Ciências Médicas de Córdoba; v. 79 n. 2 (2022); 201-204 1853-0605 0014-6722 10.31053/1853.0605.v79.n2 spa https://revistas.unc.edu.ar/index.php/med/article/view/35138/37941 https://revistas.unc.edu.ar/index.php/med/article/view/35138/37978 Derechos de autor 2022 Universidad Nacional de Córdoba http://creativecommons.org/licenses/by-nc/4.0
institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-327
container_title_str Revista de la Facultad de Ciencias Médicas de Córdoba
language Español
format Artículo revista
topic anemia, aplastic
hepatitis
coronavirus infections
anemia aplásica
hepatitis
infecciones por coronavirus
anemia aplástica
hepatite
infecções por coronavirus
spellingShingle anemia, aplastic
hepatitis
coronavirus infections
anemia aplásica
hepatitis
infecciones por coronavirus
anemia aplástica
hepatite
infecções por coronavirus
Santarelli, Ignacio Martín
Manzella, Pedro Oscar
Gasco González, Francisco
Ingold, Julián José
Olivieri, Melissa Alejandra
Cloobs Venezia, Maximiliano Ariel
Fernández, Sofía Isabel
Melero, Marcelo José
Hepatitis associated aplastic anemia during SARS-CoV-2 pandemic
topic_facet anemia, aplastic
hepatitis
coronavirus infections
anemia aplásica
hepatitis
infecciones por coronavirus
anemia aplástica
hepatite
infecções por coronavirus
author Santarelli, Ignacio Martín
Manzella, Pedro Oscar
Gasco González, Francisco
Ingold, Julián José
Olivieri, Melissa Alejandra
Cloobs Venezia, Maximiliano Ariel
Fernández, Sofía Isabel
Melero, Marcelo José
author_facet Santarelli, Ignacio Martín
Manzella, Pedro Oscar
Gasco González, Francisco
Ingold, Julián José
Olivieri, Melissa Alejandra
Cloobs Venezia, Maximiliano Ariel
Fernández, Sofía Isabel
Melero, Marcelo José
author_sort Santarelli, Ignacio Martín
title Hepatitis associated aplastic anemia during SARS-CoV-2 pandemic
title_short Hepatitis associated aplastic anemia during SARS-CoV-2 pandemic
title_full Hepatitis associated aplastic anemia during SARS-CoV-2 pandemic
title_fullStr Hepatitis associated aplastic anemia during SARS-CoV-2 pandemic
title_full_unstemmed Hepatitis associated aplastic anemia during SARS-CoV-2 pandemic
title_sort hepatitis associated aplastic anemia during sars-cov-2 pandemic
description The hepatitis-associated aplastic anemia is one of the acquired bone marrow failure syndromes. It is a stereotyped form of presentation of aplastic anemia and accounts for 2 - 5 % of the cases in the West. Its treatment, which does not differ from that of aplastic anemia, consists of immunosuppression when bone marrow transplant is not possible. Nonetheless, during the SARS-CoV-2 pandemic, recommendations restricting the use of antithymocyte globulin to those cases with the highest risk of death have been issued, since the prognosis of CoViD-19 tends to be worse if administered. We present an otherwise-healthy 18-year-old male who was diagnosed with a hepatitis-associated aplastic anemia and received a personalized treatment following these recommendations.
publisher Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
publishDate 2022
url https://revistas.unc.edu.ar/index.php/med/article/view/35138
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first_indexed 2024-09-03T21:03:14Z
last_indexed 2024-09-03T21:03:14Z
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