Pro-oxidant effects induced by 17β-estradiol promote p53 and p21 activation in normal and tumoral pituitary cells

Abstract:  The estrogenic action on pituitary cell growth is widely known. We have previously demonstrated the activation of the antioxidant pathway of phosphorylated erythroid 2-derived nuclear factor 2 (p-Nrf2) in response to DNA damage by 17β-estradiol (E2). In this study we analyze...

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Autores principales: Grondona , E, Venier , AC, Sosa , LDV, Pesaola , F, Fernandez , S, Sabatino , ME, Gutiérrez , S, De Paul, AL
Formato: Artículo revista
Publicado: Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2021
Materias:
P53
P21
p53
p21
.
Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/35080
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