Pneumonia in h1 n1 flu infection patients

In March 2009, there was an outbreak of respiratory illness, later identified as caused by Influenza A (H1N1); the affected patients can develop severe lower respiratory infections. Objective: To describe the characteristics of 14 patients admitted to Hospital Córdoba diagnosed with H1N1 Influenza-a...

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Autores principales: Tarán, Mariana, Igarzabal, Pablo, Bergallo, Carlos, Riera, Fernando
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2009
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Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/23462
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id I10-R327-article-23462
record_format ojs
institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-327
container_title_str Revista de la Facultad de Ciencias Médicas de Córdoba
language Español
format Artículo revista
topic Influenza A virus
H1N1 Subtype
Pneumonia
Subtipo H1N1 del Virus de la Influenza A
virus de la Influenza A
Neumonía
spellingShingle Influenza A virus
H1N1 Subtype
Pneumonia
Subtipo H1N1 del Virus de la Influenza A
virus de la Influenza A
Neumonía
Tarán, Mariana
Igarzabal, Pablo
Bergallo, Carlos
Riera, Fernando
Pneumonia in h1 n1 flu infection patients
topic_facet Influenza A virus
H1N1 Subtype
Pneumonia
Subtipo H1N1 del Virus de la Influenza A
virus de la Influenza A
Neumonía
author Tarán, Mariana
Igarzabal, Pablo
Bergallo, Carlos
Riera, Fernando
author_facet Tarán, Mariana
Igarzabal, Pablo
Bergallo, Carlos
Riera, Fernando
author_sort Tarán, Mariana
title Pneumonia in h1 n1 flu infection patients
title_short Pneumonia in h1 n1 flu infection patients
title_full Pneumonia in h1 n1 flu infection patients
title_fullStr Pneumonia in h1 n1 flu infection patients
title_full_unstemmed Pneumonia in h1 n1 flu infection patients
title_sort pneumonia in h1 n1 flu infection patients
description In March 2009, there was an outbreak of respiratory illness, later identified as caused by Influenza A (H1N1); the affected patients can develop severe lower respiratory infections. Objective: To describe the characteristics of 14 patients admitted to Hospital Córdoba diagnosed with H1N1 Influenza-associated pneumonia during July and August of 2009. Material and Methods: We analyzed patients admitted between 26/06/09 and 08/09/2009 with diagnosis of community-acquired pneumonia. All patients were conducted laboratory, chest X-ray, blood and nasal swab for viral isolation by polymerase chain reaction (real-time RT-PCR), beginning treatment with sulbactam ampicillin, clarithromycin, and oseltamivir. Results: The number of patients studied was 44 patients, in 14 patients was confirmed the diagnosis of influenza by RT-PCR, the median age was 44 years (range 18 to 81 years) and 9 (64%) were female. The average time between onset of symptoms and medical consultation was 5 days and the average hospital stay was 6 days. Clinical symptoms: fever over 38 C, 13 patients (92%), dry cough, 4 patients (28%), productive cough, 9 (64%), headache and myalgia: 6. Radiological presentation 10 (72%) patients had bilateral involvement, both bases, and two or more quadrants involved in the chest X-ray. Co morbilities: one patient had heart disease and one patient had COPD. Risk factors: 3 patients were alcoholic, 4 patients were smokers, and 2 postpartum. A single patient with H1N1 required mechanical ventilation and died. Conclusion: pneumonia influenza (H1N1) can cause bilateral commitment, affect healthy patients at a younger age.
publisher Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
publishDate 2009
url https://revistas.unc.edu.ar/index.php/med/article/view/23462
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AT rierafernando pneumoniainh1n1fluinfectionpatients
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spelling I10-R327-article-234622024-08-27T18:24:27Z Pneumonia in h1 n1 flu infection patients Neumonías en pacientes con gripe Tarán, Mariana Igarzabal, Pablo Bergallo, Carlos Riera, Fernando Influenza A virus H1N1 Subtype Pneumonia Subtipo H1N1 del Virus de la Influenza A virus de la Influenza A Neumonía In March 2009, there was an outbreak of respiratory illness, later identified as caused by Influenza A (H1N1); the affected patients can develop severe lower respiratory infections. Objective: To describe the characteristics of 14 patients admitted to Hospital Córdoba diagnosed with H1N1 Influenza-associated pneumonia during July and August of 2009. Material and Methods: We analyzed patients admitted between 26/06/09 and 08/09/2009 with diagnosis of community-acquired pneumonia. All patients were conducted laboratory, chest X-ray, blood and nasal swab for viral isolation by polymerase chain reaction (real-time RT-PCR), beginning treatment with sulbactam ampicillin, clarithromycin, and oseltamivir. Results: The number of patients studied was 44 patients, in 14 patients was confirmed the diagnosis of influenza by RT-PCR, the median age was 44 years (range 18 to 81 years) and 9 (64%) were female. The average time between onset of symptoms and medical consultation was 5 days and the average hospital stay was 6 days. Clinical symptoms: fever over 38 C, 13 patients (92%), dry cough, 4 patients (28%), productive cough, 9 (64%), headache and myalgia: 6. Radiological presentation 10 (72%) patients had bilateral involvement, both bases, and two or more quadrants involved in the chest X-ray. Co morbilities: one patient had heart disease and one patient had COPD. Risk factors: 3 patients were alcoholic, 4 patients were smokers, and 2 postpartum. A single patient with H1N1 required mechanical ventilation and died. Conclusion: pneumonia influenza (H1N1) can cause bilateral commitment, affect healthy patients at a younger age. Durante marzo de 2009, se presentó un brote de enfermedad respiratoria, identificado posteriormente como causado por Influenza A (H1N1); los pacientes afectados pueden desarrollar infecciones respiratorias bajas severas. Objetivo: describir las características de 14 pacientes ingresados al Hospital Córdoba con diagnóstico de neumonía asociada a Influenza H1N1 durante julio y agosto del año 2009.Material y Método: Se analizaron pacientes ingresados entre el 26/06/09 y el 09/08/09 con diagnóstico de Neumonía adquirida de la comunidad. A todos los pacientes se les realizó laboratorio, Rx de tórax, hemocultivos e hisopado nasal/faríngeo para aislamiento viral mediante la reacción en cadena de polimerasa en tiempo real (PCR-RT); instaurándose tratamiento con ampicilina sulbactam, claritromicina y oseltamivir. Resultados: El número de pacientes estudiados fue de 44 pacientes, en 14 se confirmó el diagnóstico de gripe por PCR-RT, la mediana de la edad fue 44 años (rango entre 18 y 81 años) 9(64%) sexo femenino. El tiempo promedio entre el inicio de los síntomas y la consulta fue de 5 días y el promedio de internación fue de 6 días. Síntomas clínicos: fiebre mayor de 38 C, 13 pacientes (92%), Tos seca 4 pacientes (28%), tos productiva 9 (64%), Cefalea y mialgias: 6. Presentación Radiologíca 10 (72 %) pacientes tenían compromiso bilateral, preferentemente bibasal y 2 ó más cuadrantes comprometidos en la radiografía. Co morbilidades: 1 paciente cardiopatía y 1 paciente EPOC. Factores de riesgo: 3 pacientes alcoholistas, 4 tabaquistas y 2 pacientes puérperas. Un solo paciente con H1N1 requirió ventilación mecánica y falleció.Conclusión: la neumonía por influenza (H1N1) puede causar compromiso bilateral, afectar a pacientes sanos y a una edad más temprana. Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2009-09-12 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.unc.edu.ar/index.php/med/article/view/23462 10.31053/1853.0605.v66.n3.23462 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 66 No. 3 (2009); 113-117 Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 66 Núm. 3 (2009); 113-117 Revista da Faculdade de Ciências Médicas de Córdoba; v. 66 n. 3 (2009); 113-117 1853-0605 0014-6722 10.31053/1853.0605.v66.n3 spa https://revistas.unc.edu.ar/index.php/med/article/view/23462/23208 Derechos de autor 2009 Universidad Nacional de Córdoba https://creativecommons.org/licenses/by-nc/4.0