Fetal exposure to bisphenol A: Presence of bisphenol A in urine of pregnant women assisted in a hospital in the City of Buenos Aires. Year 2013

Introduction: Bisphenol A (BPA) is an endocrine disruptor (ED)  possibly linked to adverse reproductive and neurodevelopmental effects that is used as an additive in food and beverage containers. There are no data of BPA levels in the Argentine population. The objective of this stu...

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Detalles Bibliográficos
Autores principales: Ferloni, Analía, Pereiro, Natalia, Cruz, Martín, Aragone, Soledad, Kandel Gambarte, Paula, Aliperti, Valeria, Saulino, Julia Constanza, Cambiaso, Olivia, Vázquez, Marcela Liliam, Méndez, Mariana Laura, Moix, Claudio Fernando, Vidal, Flavia Alejandra, Uicich, Raúl, Otaño, Lucas, Figar, Silvana, Giménez, María Isabel, Wahren, Carlos Gustavo
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2019
Materias:
bisphenol a
glycidyl methacrylate
pregnant women
urine
endocrine disruptors
epidemiology
environmental health.
bisfenol A glicidil metacrilato
mujeres embarazadas
orina
disruptores endocrinos
epidemiología
salud ambiental
Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/22806
Aporte de:
Revista de la Facultad de Ciencias Médicas de Córdoba de Universidad Nacional de Córdoba
Descripción
Sumario:Introduction: Bisphenol A (BPA) is an endocrine disruptor (ED)  possibly linked to adverse reproductive and neurodevelopmental effects that is used as an additive in food and beverage containers. There are no data of BPA levels in the Argentine population. The objective of this study was to measure BPA in the urine of pregnant women.  Methods: Cross-sectional study. Detection of BPA in pregnant women of the Hospital Italiano de Buenos Aires in 2013, using gas chromatography and mass spectrometry with a limit of quantification of 2 ng / ml and detection of 0.8 ng / ml. The proportion of women exposed to BPA within the 95% confidence interval (IC 95%) is described.  Results: 149 pregnant women, average age 32 years (Standard Deviation 5.3), 81% (95% CI 73.9-86.9) workers and 83.7% (95% CI 76.7-89.1) have university or higher education, 66.4% (95% CI 58-74.0) of the urinary samples were quantifiable, with a median BPA of 4.3 ng/mg Cr (RI 3.2-6.7). Conclusions: This study shows that exposure to BPA during the process of embryonic development in a sector of the population of Argentina is widespread. In Argentina, the use of this ED is only regulated in baby bottles. 

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