Primary lung Paraganglioma. A case report

Primary lung paragangliomas are rare. They are 1-2% of the paragangliomas, and most of them occur in patients of 43-61 years. They clinically appear as solitary tumors and are in general asymptomatic. These tumors show a nesting pattern (Zellballen) of chief polygonal cells locked by fibrovascular t...

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Autores principales: Kaplan, R., Burgos, A., Rodríguez, N., Meza Vetanzo, Z., Ortiz, S., Piccinni, D. J.
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2010
Materias:
tumor
paraganglioma
incidental
Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/22633
Aporte de:
Revista de la Facultad de Ciencias Médicas de Córdoba de Universidad Nacional de Córdoba
id I10-R327-article-22633
record_format ojs
spelling I10-R327-article-226332024-08-27T18:24:09Z Primary lung Paraganglioma. A case report Paraganglioma pulmonar primario como tumor incidental Kaplan, R. Burgos, A. Rodríguez, N. Meza Vetanzo, Z. Ortiz, S. Piccinni, D. J. tumor paraganglioma incidental tumor paraganglioma incidental Primary lung paragangliomas are rare. They are 1-2% of the paragangliomas, and most of them occur in patients of 43-61 years. They clinically appear as solitary tumors and are in general asymptomatic. These tumors show a nesting pattern (Zellballen) of chief polygonal cells locked by fibrovascular trabeculae with subtenticular cells. The main cells have uniform nuclei with granular eosinophilic cytoplasm, and they are positive for neuroendocrinal markers (Neuron Specific Enolase, sinaptofisine and cromogranine A). Sustentacular cells are positive for protein S-100 and neurofibrilar protein. A differential diagnosis with the carcinoid tumor can be very difficult. The surgical treatment is mandatory , specially high blood pressure and the chances of malignization. Los paragangliomas primarios pulmonares son raros. Representan el 1-2% del total de los paragangliomas, estando la mayor incidencia entre los 43 a 61 años. Clínicamente se presentan como tumores solitarios y en general son asintomáticos. Estos tumores adoptan un patrón de nidos ("zellballen”) de células principales poligonales, encerradas por trabéculas fibrovasculares con células subtenticulares. Las células principales poseen núcleos uniformes con un citoplasma eosinófilo granular y son positivas para marcadores neuroendocrinos (enolasa neuronal específica, sinaptofisina y cromogranina A). Las células subtentaculares son positivas para la proteína S-100 y proteína neurofibrilar. El diagnóstico diferencial con el tumor carcinoide pude ser muy difícil. El tratamiento quirúrgico de elección es curativo debido a la clínica, sobre todo de hipertensión arterial y a la posibilidad de malignización. Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2010-09-10 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.unc.edu.ar/index.php/med/article/view/22633 10.31053/1853.0605.v67.n3.22633 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 67 No. 3 (2010); 118-122 Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 67 Núm. 3 (2010); 118-122 Revista da Faculdade de Ciências Médicas de Córdoba; v. 67 n. 3 (2010); 118-122 1853-0605 0014-6722 10.31053/1853.0605.v67.n3 spa https://revistas.unc.edu.ar/index.php/med/article/view/22633/22250 Derechos de autor 2010 Universidad Nacional de Córdoba https://creativecommons.org/licenses/by-nc/4.0
institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-327
container_title_str Revista de la Facultad de Ciencias Médicas de Córdoba
language Español
format Artículo revista
topic tumor
paraganglioma
incidental
tumor
paraganglioma
incidental
spellingShingle tumor
paraganglioma
incidental
tumor
paraganglioma
incidental
Kaplan, R.
Burgos, A.
Rodríguez, N.
Meza Vetanzo, Z.
Ortiz, S.
Piccinni, D. J.
Primary lung Paraganglioma. A case report
topic_facet tumor
paraganglioma
incidental
tumor
paraganglioma
incidental
author Kaplan, R.
Burgos, A.
Rodríguez, N.
Meza Vetanzo, Z.
Ortiz, S.
Piccinni, D. J.
author_facet Kaplan, R.
Burgos, A.
Rodríguez, N.
Meza Vetanzo, Z.
Ortiz, S.
Piccinni, D. J.
author_sort Kaplan, R.
title Primary lung Paraganglioma. A case report
title_short Primary lung Paraganglioma. A case report
title_full Primary lung Paraganglioma. A case report
title_fullStr Primary lung Paraganglioma. A case report
title_full_unstemmed Primary lung Paraganglioma. A case report
title_sort primary lung paraganglioma. a case report
description Primary lung paragangliomas are rare. They are 1-2% of the paragangliomas, and most of them occur in patients of 43-61 years. They clinically appear as solitary tumors and are in general asymptomatic. These tumors show a nesting pattern (Zellballen) of chief polygonal cells locked by fibrovascular trabeculae with subtenticular cells. The main cells have uniform nuclei with granular eosinophilic cytoplasm, and they are positive for neuroendocrinal markers (Neuron Specific Enolase, sinaptofisine and cromogranine A). Sustentacular cells are positive for protein S-100 and neurofibrilar protein. A differential diagnosis with the carcinoid tumor can be very difficult. The surgical treatment is mandatory , specially high blood pressure and the chances of malignization.
publisher Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
publishDate 2010
url https://revistas.unc.edu.ar/index.php/med/article/view/22633
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AT burgosa primarylungparagangliomaacasereport
AT rodriguezn primarylungparagangliomaacasereport
AT mezavetanzoz primarylungparagangliomaacasereport
AT ortizs primarylungparagangliomaacasereport
AT piccinnidj primarylungparagangliomaacasereport
AT kaplanr paragangliomapulmonarprimariocomotumorincidental
AT burgosa paragangliomapulmonarprimariocomotumorincidental
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AT ortizs paragangliomapulmonarprimariocomotumorincidental
AT piccinnidj paragangliomapulmonarprimariocomotumorincidental
first_indexed 2024-09-03T21:00:25Z
last_indexed 2024-09-03T21:00:25Z
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