Microbiota-immune-brain interactions
The Research increasingly shows that the gut microbiota not only influences the development and functions of the digestive system, but also plays a key role in the communication between the gut and the brain. Growing evidence highlights the role of the immune system in this complex network of intera...
Guardado en:
| Autores principales: | , |
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| Formato: | Artículo revista |
| Lenguaje: | Inglés Español |
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Asociación de Medicina del Estrés y Psicoinmunoneuroendocrinología
2025
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| Acceso en línea: | https://revistas.unc.edu.ar/index.php/pinelatam/article/view/51280 |
| Aporte de: |
| Sumario: | The Research increasingly shows that the gut microbiota not only influences the development and functions of the digestive system, but also plays a key role in the communication between the gut and the brain. Growing evidence highlights the role of the immune system in this complex network of interactions. Microbial metabolites, such as short-chain fatty acids, help maintain immune balance, protect the blood–brain barrier, and affect both neurons and glial cells. When this balance is disrupted, as it occurs in dysbiosis, it can contribute to neurological diseases. Although most findings come from experimental studies and should therefore be interpreted with caution, probiotics, prebiotics, and postbiotics appear to be promising therapeutic strategies. This new “microbiota–immune–brain” model offers exciting perspectives for preventing and treating psychiatric and neurological disorders, such as Parkinson’s disease, although larger clinical trials are still needed to confirm its effectiveness in humans. |
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