Dialogue between the gut and the mind

The Psycho-Immuno-Neuro-Endocrinology (PINE/PNIE) was built on the shoulders of great pioneers, where the word integration expands as a concept not only in the bio-medical area but also in the social, political, economic and religious fields. Integration as a concept of uniting, incorporating and in...

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Autor principal: Rovasio, Roberto A.
Formato: Artículo revista
Lenguaje:Español
Publicado: Asociación de Medicina del Estrés y Psicoinmunoneuroendocrinología 2022
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Acceso en línea:https://revistas.unc.edu.ar/index.php/pinelatam/article/view/38630
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Sumario:The Psycho-Immuno-Neuro-Endocrinology (PINE/PNIE) was built on the shoulders of great pioneers, where the word integration expands as a concept not only in the bio-medical area but also in the social, political, economic and religious fields. Integration as a concept of uniting, incorporating and intertwining apparently alien or divergent parts to assimilate them into a whole. This article tries to spread the PINE/PNIE concept through an example of that interaction. Before the last third of the 20th century ‒baptism of the PINE/PNIE‒ the idea of a functional relationship between intestine, brain and psyche, would have provoked indulgent smiles, limiting those of witchcraft or pseudoscience. Today, in-depth research has dispelled doubts and shown verifiable and verified evidence of "messages" (molecular signals) that travel and interact among systems of such dissimilar types as the digestive, neural and immune systems, among others. The dialogue that is reported among cells of the digestive (and their "tenants"), endocrine, central and peripheral nervous systems, with its extension to behavioral aspects (the "mind"), is just one sample among many that, just to mention them, would exceed the space reasonably available.