Simple sequence repeats together with mismatch repair deficiency can bias mutagenic pathways in Pseudomonas aeruginosa during chronic lung infection

Pseudomonas aeruginosa is an opportunistic pathogen that chronically infects the airways of cystic fibrosis (CF) patients and undergoes a process of genetic adaptation based on mutagenesis. We evaluated the role of mononucleotide G:C and A:T simple sequence repeats (SSRs) in this adaptive process....

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Autores principales: Moyano, Alejandro J., Feliziani, Sofía, Di Rienzo, Julio Alejandro, Smania, Andrea M.
Formato: article
Lenguaje:Inglés
Publicado: 2022
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Acceso en línea:http://hdl.handle.net/11086/23817
https://doi.org/10.1371/journal.pone.0080514
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