Effects of the L-arginine supplementation in the fetal development alterations in a congenital chagas disease mouse model

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Detalles Bibliográficos
Autores principales:	Díaz Luján, Cintia, Piegari, Mariana, Glocker, Mónica, Triquell, María Fernanda, Mezzano, Luciana, Fretes, Ricardo Emilio
Formato:	conferenceObject
Lenguaje:	Inglés
Publicado:	2022
Materias:	Congenital chagas disease Fetal develompment Trypanosoma cruzi L-Arginine Protein restriction
Acceso en línea:	http://hdl.handle.net/11086/27642
Aporte de:	Repositorio Digital Universitario (UNC) de Universidad Nacional de Córdoba

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spelling	I10-R141-11086-276422023-08-30T14:09:10Z Effects of the L-arginine supplementation in the fetal development alterations in a congenital chagas disease mouse model Díaz Luján, Cintia Piegari, Mariana Glocker, Mónica Triquell, María Fernanda Mezzano, Luciana Fretes, Ricardo Emilio Congenital chagas disease Fetal develompment Trypanosoma cruzi L-Arginine Protein restriction 1 p. Fil: Díaz Luján, Cintia. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Cátedra de Biología Celular, Histología y Embriología; Argentina. Fil: Piegari, Mariana. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Cátedra de Biología Celular, Histología y Embriología; Argentina. Fil: Glocker, Mónica. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Cátedra de Biología Celular, Histología y Embriología; Argentina. Fil: Triquell, María Fernanda. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Cátedra de Biología Celular, Histología y Embriología; Argentina. Fil: Mezzano, Luciana. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Cátedra de Biología Celular, Histología y Embriología; Argentina. Fil: Fretes, Ricardo Emilio. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Cátedra de Biología Celular, Histología y Embriología; Argentina. Fil: Fretes, Ricardo Emilio. Universidad Nacional de La Rioja. Histología y Embriología. Instituto de Investigaciones en Ciencias de la Salud Humana; Argentina. A nutritional protein deficit would induce modifications in fetal development, parasitemia and congenital Chagas transmission, while arginine intake would improve this situation. Female mice (C3H strain) were feeded with hypoproteic (H), and normoproteic (N) diets during a month, some of them were provided also with 0.1% of arginine (Arg). They were infected with Trypanosoma cruzi trypomastigotes and were sacrificed at 14th day of gestation. It was evaluated maternal parasitemia, embryos and absorptions quantity; embryos and placentae size, and uterine horns weight. The H diet increased infection effects, affecting fetal development and maternal parasitemia. Arg improved protective effects, with fetal size increment, reduced embryo absorptions and maternal parasitemia. The high incidence of pregnant women affected with Chagas disease are related to deficient diets that would affect fetal development, and would be associated with susceptibility to congenital transmission. The Arg supplementation improve fetal development in the acute phase of Chagas infection, possible due to the nourishment increment including sources for nitric oxide production http://www.placentajournal.org/article Fil: Díaz Luján, Cintia. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Cátedra de Biología Celular, Histología y Embriología; Argentina. Fil: Piegari, Mariana. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Cátedra de Biología Celular, Histología y Embriología; Argentina. Fil: Glocker, Mónica. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Cátedra de Biología Celular, Histología y Embriología; Argentina. Fil: Triquell, María Fernanda. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Cátedra de Biología Celular, Histología y Embriología; Argentina. Fil: Mezzano, Luciana. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Cátedra de Biología Celular, Histología y Embriología; Argentina. Fil: Fretes, Ricardo Emilio. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Cátedra de Biología Celular, Histología y Embriología; Argentina. Fil: Fretes, Ricardo Emilio. Universidad Nacional de La Rioja. Histología y Embriología. Instituto de Investigaciones en Ciencias de la Salud Humana; Argentina. 2022-07-28T15:05:51Z 2022-07-28T15:05:51Z 2013 conferenceObject http://hdl.handle.net/11086/27642 eng Attribution-NonCommercial-ShareAlike 4.0 International https://creativecommons.org/licenses/by-nc-sa/4.0/ Impreso; Electrónico y/o Digital
institution	Universidad Nacional de Córdoba
institution_str	I-10
repository_str	R-141
collection	Repositorio Digital Universitario (UNC)
language	Inglés
topic	Congenital chagas disease Fetal develompment Trypanosoma cruzi L-Arginine Protein restriction
spellingShingle	Congenital chagas disease Fetal develompment Trypanosoma cruzi L-Arginine Protein restriction Díaz Luján, Cintia Piegari, Mariana Glocker, Mónica Triquell, María Fernanda Mezzano, Luciana Fretes, Ricardo Emilio Effects of the L-arginine supplementation in the fetal development alterations in a congenital chagas disease mouse model
topic_facet	Congenital chagas disease Fetal develompment Trypanosoma cruzi L-Arginine Protein restriction
description	1 p.
format	conferenceObject
author	Díaz Luján, Cintia Piegari, Mariana Glocker, Mónica Triquell, María Fernanda Mezzano, Luciana Fretes, Ricardo Emilio
author_facet	Díaz Luján, Cintia Piegari, Mariana Glocker, Mónica Triquell, María Fernanda Mezzano, Luciana Fretes, Ricardo Emilio
author_sort	Díaz Luján, Cintia
title	Effects of the L-arginine supplementation in the fetal development alterations in a congenital chagas disease mouse model
title_short	Effects of the L-arginine supplementation in the fetal development alterations in a congenital chagas disease mouse model
title_full	Effects of the L-arginine supplementation in the fetal development alterations in a congenital chagas disease mouse model
title_fullStr	Effects of the L-arginine supplementation in the fetal development alterations in a congenital chagas disease mouse model
title_full_unstemmed	Effects of the L-arginine supplementation in the fetal development alterations in a congenital chagas disease mouse model
title_sort	effects of the l-arginine supplementation in the fetal development alterations in a congenital chagas disease mouse model
publishDate	2022
url	http://hdl.handle.net/11086/27642
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Effects of the L-arginine supplementation in the fetal development alterations in a congenital chagas disease mouse model

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