Dissolution properties, solid-state transformation and polymorphic crystallization: progesterone case study

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Progesterone is a natural steroid hormone and a poor soluble drug which presents two polymorphs (forms 1 and 2). Different methods to obtain form 2 were tested and a complete solid-state characterization of both polymorphs (forms 1 and 2) was conducted. X-ray powder diffraction, hot stage microsc...

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Autores principales: Araya-Sibaja, Andrea Mariela, Paulino, Amarilis Scremin, Rauber, Gabriela Schneider, Maduro Campos, Carlos Eduardo, Cardoso, Simone Gonçalves, Monti, Gustavo Alberto, Heredia, Valeria, Bianco, Ismael Darío, Beltramo, Dante Miguel, Cuffini, Silvia Lucía
Formato: article
Lenguaje:Inglés
Publicado: 2022
Materias:
Intrinsic disolution rate
Phase transformation
Polymorphism
Progesterone
Acceso en línea:http://hdl.handle.net/11086/25007
https://doi.org/10.3109/10837450.2013.829096
https://doi.org/10.3109/10837450.2013.829096
Aporte de:
Repositorio Digital Universitario (UNC) de Universidad Nacional de Córdoba

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