Constitutive hippocampal cholesterol loss underlies poor cognition in old rodents

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Cognitive decline is one of the many characteristics of aging. Reduced long-term potentiation (LTP) and long-term depression (LTD) are thought to be responsible for this decline, although the precise mechanisms underlying LTP and LTD dampening in the old remain unclear. We previously showed that agi...

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Detalles Bibliográficos
Autores principales: Martín, Mauricio Gerardo, Ahmed, Tariq, Korovaichuk, Alejandra, Venero, César, Menchón, Silvia Adriana, Salas, Isabel, Munck, Sebastian, Herreras, Oscar, Balschun, Detlef, Dotti, Carlos Gerardo
Formato: article
Lenguaje:Inglés
Publicado: 2021
Materias:
Aging
Cholesterol
Learning
LTD
PI3K
Neuroscience
Long-term depression
Acceso en línea:http://hdl.handle.net/11086/20817
https://doi.org/10.15252/emmm.201303711
Aporte de:
Repositorio Digital Universitario (UNC) de Universidad Nacional de Córdoba

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