Use in the real world of Aspirin 100 mg in high risk pregnancies to prevent Preeclampsia.

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Objectives The objective of the present study was to analyse the use of 100 g aspirin dose as prevention method for preeclampsia in high risk pregnant patients. Methods A retrospective cohort study was performed in high risk pregnant patients with a blood pressure protocol, and the use of 100 mg of...

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Autores principales: Espeche, Walter Gaston, Minetto, Julian, Salazar, Martin Rogelio
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2022
Materias:
preeclampsia
eclampsia
hypertension
pregnancy
aspirin
embarazo
hipertension
aspirina
Pré-eclâmpsia
Hipertensão
gravidez
Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/32783
Aporte de:
Revistas de la UNC de Universidad Nacional de Córdoba
id I10-R10article-32783
record_format ojs
institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-10
container_title_str Revistas de la UNC
language Español
format Artículo revista
topic preeclampsia
eclampsia
hypertension
pregnancy
aspirin
preeclampsia
eclampsia
embarazo
hipertension
aspirina
Pré-eclâmpsia
eclampsia
Hipertensão
gravidez
aspirina
spellingShingle preeclampsia
eclampsia
hypertension
pregnancy
aspirin
preeclampsia
eclampsia
embarazo
hipertension
aspirina
Pré-eclâmpsia
eclampsia
Hipertensão
gravidez
aspirina
Espeche, Walter Gaston
Minetto, Julian
Salazar, Martin Rogelio
Use in the real world of Aspirin 100 mg in high risk pregnancies to prevent Preeclampsia.
topic_facet preeclampsia
eclampsia
hypertension
pregnancy
aspirin
preeclampsia
eclampsia
embarazo
hipertension
aspirina
Pré-eclâmpsia
eclampsia
Hipertensão
gravidez
aspirina
author Espeche, Walter Gaston
Minetto, Julian
Salazar, Martin Rogelio
author_facet Espeche, Walter Gaston
Minetto, Julian
Salazar, Martin Rogelio
author_sort Espeche, Walter Gaston
title Use in the real world of Aspirin 100 mg in high risk pregnancies to prevent Preeclampsia.
title_short Use in the real world of Aspirin 100 mg in high risk pregnancies to prevent Preeclampsia.
title_full Use in the real world of Aspirin 100 mg in high risk pregnancies to prevent Preeclampsia.
title_fullStr Use in the real world of Aspirin 100 mg in high risk pregnancies to prevent Preeclampsia.
title_full_unstemmed Use in the real world of Aspirin 100 mg in high risk pregnancies to prevent Preeclampsia.
title_sort use in the real world of aspirin 100 mg in high risk pregnancies to prevent preeclampsia.
description Objectives The objective of the present study was to analyse the use of 100 g aspirin dose as prevention method for preeclampsia in high risk pregnant patients. Methods A retrospective cohort study was performed in high risk pregnant patients with a blood pressure protocol, and the use of 100 mg of aspirin vs. its non-use was evaluated in the incidence of PREEC.  Estimations between the two groups were performed with and without variable adjustment by means of binary logistic regression models. Results 633 high risk pregnant patients were evaluated. The average age was 30±7 years old, and 25±8 weeks of pregnancy. 281 women (44.3 %) within this group received aspirin. The total prevalence of PREEC in our sample was 151 pregnant women (23.8 %).Pregnant patients under the aspirin treatment developed less PREEC events (19.2% vs 27.5%, p=0.019); with OR not adjusted 0.62 (IC95% 0.43-0.91 p= 0.017). The risk was similar when it was adjusted by age, preeclampsia history, diabetes mellitus and chronic high blood pressure. (OR adjusted 0.63 IC95% 0.43-0.92 p= 0.017). Conclusions The use of 100 mg of aspirin a day before the 20th week of pregnancy in high risk pregnant patients decreased the risk of developing PREEC, regardless the age and risk factors.
publisher Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
publishDate 2022
url https://revistas.unc.edu.ar/index.php/med/article/view/32783
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