Mortality and recurrence of venous thromboembolic disease in adult patients: prospective cohort

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INTRODUCTION: Venous thromboembolic disease (VTE) is a pathology that increases with age. OBJECTIVE: to compare the survival of the elderly and the young with a first episode of acute and symptomatic VTE. MATERIALS AND METHODS: Prospective cohort of incident VTE cases included in the Institutional R...

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Autores principales: Posadas-Martinez, Maria Lourdes, Pagotto, Vanina Laura, Grande Ratti, Maria Florencia, Alfie, Veronica, Andresik, Diego, Torres Gomez, Felipe, Giunta, Diego Hernan, Luxardo, Rosario, Scolnik, Marina, Vazquez, Fernando Javier
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2020
Materias:
tromboembolia
tromboembolia venosa
anciano
español
english
portugues
Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/27135
Aporte de:
Revistas de la UNC de Universidad Nacional de Córdoba
id I10-R10article-27135
record_format ojs
institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-10
container_title_str Revistas de la UNC
language Español
format Artículo revista
topic tromboembolia
tromboembolia venosa
anciano
español
english
portugues
spellingShingle tromboembolia
tromboembolia venosa
anciano
español
english
portugues
Posadas-Martinez, Maria Lourdes
Pagotto, Vanina Laura
Grande Ratti, Maria Florencia
Alfie, Veronica
Andresik, Diego
Torres Gomez, Felipe
Giunta, Diego Hernan
Luxardo, Rosario
Scolnik, Marina
Vazquez, Fernando Javier
Mortality and recurrence of venous thromboembolic disease in adult patients: prospective cohort
topic_facet tromboembolia
tromboembolia venosa
anciano
español
english
portugues
author Posadas-Martinez, Maria Lourdes
Pagotto, Vanina Laura
Grande Ratti, Maria Florencia
Alfie, Veronica
Andresik, Diego
Torres Gomez, Felipe
Giunta, Diego Hernan
Luxardo, Rosario
Scolnik, Marina
Vazquez, Fernando Javier
author_facet Posadas-Martinez, Maria Lourdes
Pagotto, Vanina Laura
Grande Ratti, Maria Florencia
Alfie, Veronica
Andresik, Diego
Torres Gomez, Felipe
Giunta, Diego Hernan
Luxardo, Rosario
Scolnik, Marina
Vazquez, Fernando Javier
author_sort Posadas-Martinez, Maria Lourdes
title Mortality and recurrence of venous thromboembolic disease in adult patients: prospective cohort
title_short Mortality and recurrence of venous thromboembolic disease in adult patients: prospective cohort
title_full Mortality and recurrence of venous thromboembolic disease in adult patients: prospective cohort
title_fullStr Mortality and recurrence of venous thromboembolic disease in adult patients: prospective cohort
title_full_unstemmed Mortality and recurrence of venous thromboembolic disease in adult patients: prospective cohort
title_sort mortality and recurrence of venous thromboembolic disease in adult patients: prospective cohort
description INTRODUCTION: Venous thromboembolic disease (VTE) is a pathology that increases with age. OBJECTIVE: to compare the survival of the elderly and the young with a first episode of acute and symptomatic VTE. MATERIALS AND METHODS: Prospective cohort of incident VTE cases included in the Institutional Registry of Venous Thromboembolic Disease (NCT01372514) of the Italian Hospital of Buenos Aires between 2012-2014, divided into young groups (17-64 years old) and elderly (65 years old). All the patients were followed annually to assess the time to recurrence (progression or new symptomatic event of VTE) as competitive events in the context of death and major bleeding. Raw (c) and adjusted (a) risks were presented. RESULTS: 446 patients were included, 63% (292) were older than 65 years. Survival was lower in the elderly compared to the young (p 0.007), at 3 months 87% vs. 95% and at one year 73% vs. 87%, respectively. The elderly had a HRc1.71 and HR at 1.68. The overall recurrence was 5% (95% CI 3-8) at one month, 6% (95% CI 4-9) at 3 months, 8% (95% CI). 6-11) at one year and 13% (95% CI 9-18) at two years. No association was found between age and recurrence sub hazard 0.8 (CI 0.34-1.86). Bleeding occurred in 9% (39) of the patients. CONCLUSIONS: The overall mortality in patients with confirmed VTE is higher in the elderly population. There were no differences in relation to the recurrence of VTE, or bleeding, and neither with age.
publisher Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
publishDate 2020
url https://revistas.unc.edu.ar/index.php/med/article/view/27135
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