Relationship between the values of specific prostate antigen and the score de Gleason in the adenocarcinoma acinar cell of prostate

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Currently, prostate adenocarcinoma is considered a health problem of great relevance since it constitutes the second cause of morbidity and mortality among men over 50 in the Western Hemisphere. One of the methods for its early detection is to determine the serum values ​​of the prostate antigen. Th...

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Autores principales: Martinez, EM, Alcain, WL, Imahorn, J, Saavedra, NA, Negri , I, Cremonezzi, DC, Cabalier, ME
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2019
Materias:
prostate cancer
score gleason
PSA
Cáncer de próstata
score de gleason
Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/26172
Aporte de:
Revistas de la UNC de Universidad Nacional de Córdoba
id I10-R10article-26172
record_format ojs
institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-10
container_title_str Revistas de la UNC
language Español
format Artículo revista
topic prostate cancer
score gleason
PSA
Cáncer de próstata
score de gleason
PSA
spellingShingle prostate cancer
score gleason
PSA
Cáncer de próstata
score de gleason
PSA
Martinez, EM
Alcain, WL
Imahorn, J
Saavedra, NA
Negri , I
Cremonezzi, DC
Cabalier, ME
Relationship between the values of specific prostate antigen and the score de Gleason in the adenocarcinoma acinar cell of prostate
topic_facet prostate cancer
score gleason
PSA
Cáncer de próstata
score de gleason
PSA
author Martinez, EM
Alcain, WL
Imahorn, J
Saavedra, NA
Negri , I
Cremonezzi, DC
Cabalier, ME
author_facet Martinez, EM
Alcain, WL
Imahorn, J
Saavedra, NA
Negri , I
Cremonezzi, DC
Cabalier, ME
author_sort Martinez, EM
title Relationship between the values of specific prostate antigen and the score de Gleason in the adenocarcinoma acinar cell of prostate
title_short Relationship between the values of specific prostate antigen and the score de Gleason in the adenocarcinoma acinar cell of prostate
title_full Relationship between the values of specific prostate antigen and the score de Gleason in the adenocarcinoma acinar cell of prostate
title_fullStr Relationship between the values of specific prostate antigen and the score de Gleason in the adenocarcinoma acinar cell of prostate
title_full_unstemmed Relationship between the values of specific prostate antigen and the score de Gleason in the adenocarcinoma acinar cell of prostate
title_sort relationship between the values of specific prostate antigen and the score de gleason in the adenocarcinoma acinar cell of prostate
description Currently, prostate adenocarcinoma is considered a health problem of great relevance since it constitutes the second cause of morbidity and mortality among men over 50 in the Western Hemisphere. One of the methods for its early detection is to determine the serum values ​​of the prostate antigen. The tumor histological grade in these neoplasms constitutes a prognostic factor for therapeutic decision making.   The objective of this investigation was to determine the relationship between the Gleason Score and the values ​​of prostate specific antigen in biopsies of invasive acinar adenocarcinoma of the prostate. This is an observational, cross-sectional, retrospective and population-based study, where 78 cases of prostate biopsies obtained from the archives of the Service and 1st Pathology Department of the National Hospital of Clinics, of the city of Córdoba, were selected puncture between July 2017 and May 2019 with a diagnosis of invasive acinar adenocarcinoma of the prostate, which presented a complete clinical history performed in said hospital, together with a thorough physical examination. Of the 78 cases analyzed, 29 presented a diagnosis of invasive acinar adenocarcinoma of the prostate with a high Gleason Score of 8 or more. They were related to a specific prostate antigen value above 10 ng / dl (72%). Furthermore, it was observed that in those cases in which the antigen values ​​were high and had an adenocarcinoma with a Gleason score below 6 (67%), they were related to varying degrees of exacerbated chronic prostatitis. The realization of this work allows to establish that a high value of prostate specific antigen could be related to a high Gleason Score and therefore this determination would have predictive value of the prognosis in this variant of prostate carcinoma.
publisher Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
publishDate 2019
url https://revistas.unc.edu.ar/index.php/med/article/view/26172
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