Respiratory infection with human bocavirus 1. Report of a case of viral pneumonia in an infant without comorbidity
Abstract: Human Bocavirus-1/HBoV1 causes acute respiratory infections/ARI (bronchiolitis/pneumonia) mostly in young children. It was identified in 2005 and has not yet been incorporated into the routine virus screening in ARI. Symptoms of viral pneumonia in children less than 2 years...
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Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
2021
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| Acceso en línea: | https://revistas.unc.edu.ar/index.php/med/article/view/34867 |
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I10-R10-article-34867 |
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Universidad Nacional de Córdoba |
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Revistas de la UNC |
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Artículo revista |
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Human Bocavirus-1 infant pneumonia lower respiratory tract infections Bocavirus Humano 1 lactante neumonía infección respiratoria aguda baja . |
| spellingShingle |
Human Bocavirus-1 infant pneumonia lower respiratory tract infections Bocavirus Humano 1 lactante neumonía infección respiratoria aguda baja . Boggio , GA Montañez Sandoz , A Abbiatti , G Musacchio , NN Provenzani , LM Salvetti , MB Adamo , MP Moreno , LB Respiratory infection with human bocavirus 1. Report of a case of viral pneumonia in an infant without comorbidity |
| topic_facet |
Human Bocavirus-1 infant pneumonia lower respiratory tract infections Bocavirus Humano 1 lactante neumonía infección respiratoria aguda baja . |
| author |
Boggio , GA Montañez Sandoz , A Abbiatti , G Musacchio , NN Provenzani , LM Salvetti , MB Adamo , MP Moreno , LB |
| author_facet |
Boggio , GA Montañez Sandoz , A Abbiatti , G Musacchio , NN Provenzani , LM Salvetti , MB Adamo , MP Moreno , LB |
| author_sort |
Boggio , GA |
| title |
Respiratory infection with human bocavirus 1. Report of a case of viral pneumonia in an infant without comorbidity |
| title_short |
Respiratory infection with human bocavirus 1. Report of a case of viral pneumonia in an infant without comorbidity |
| title_full |
Respiratory infection with human bocavirus 1. Report of a case of viral pneumonia in an infant without comorbidity |
| title_fullStr |
Respiratory infection with human bocavirus 1. Report of a case of viral pneumonia in an infant without comorbidity |
| title_full_unstemmed |
Respiratory infection with human bocavirus 1. Report of a case of viral pneumonia in an infant without comorbidity |
| title_sort |
respiratory infection with human bocavirus 1. report of a case of viral pneumonia in an infant without comorbidity |
| description |
Abstract:
Human Bocavirus-1/HBoV1 causes acute respiratory infections/ARI (bronchiolitis/pneumonia) mostly in young children. It was identified in 2005 and has not yet been incorporated into the routine virus screening in ARI. Symptoms of viral pneumonia in children less than 2 years old are often interpreted as of bacterial etiology, leading to unnecessary administration of antibiotics. Objective: to report the case of a previously healthy infant who developed HBoV1 pneumonia without complications, in order to consider HBoV1 as one of the possible agents involved.
Clinical case. 19-month-old female, full-term/2780 grams. No relevant personal or familiar pathological history; complete vaccination.
Reason for consultation: fever, cough, and shortness of breath. Antecedents: 3 days before, she started with rhinitis and dry cough. She had a fever peak of 38.7°C, so her pediatrician prescribed oral amoxicillin. On Apr/26/2021 she went to the emergency service due to persistent fever and worsening cough. Mild/moderate respiratory distress was observed; inhaled adrenergic drugs were administered, with good clinical response and outpatient follow-up (prior swabbing for COVID-19). The next day, she returned with food rejection and was hospitalized. Laboratory: hemoglobin 10.9g/dl, hematocrit 34%; leukocytes: 15,380 (69/15/15); platelets 299,000/ml; gases: 7.48/27.2/84.2/19.9/-2.1); ionogram Na 134/K 4/Cl 100; CRP: 17.8. Chest X-ray compatible with viral pneumonia. O2 saturation: 93%. Amoxicillin was suspended; hydration, oxygen by nasal cannula (3 liters/min) and inhaled salbutamol were administered. The complete panel of respiratory viruses was negative (RSV, Parainfluenza 1-3, Metapneumovirus, Influenza A/B and Adenovirus by IF; PCR for COVID-19: negative). HBoV1 detected in nasal secretions and serum (PCR with high viral load/>1x106 c.gen/mL) was the only positive finding. Evolution: 48 hours after admission she was afebrile; O2 saturation 95%; supplementary oxygen therapy was suspended. Patient was discharged without complications. In the follow-up (10 days) she did not show relapses or respiratory symptoms, so aerosol therapy was suspended.
Conclusions. A case of HBoV1 infection in an infant with no comorbidity is reported. Recognition of the viral etiology in hospitalized cases of pneumonia contributes to optimize the clinical management of patients with rational use of antibiotics. HBoV1 should be included in the standard screening for respiratory infections in hospitalized infants.
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| publisher |
Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología |
| publishDate |
2021 |
| url |
https://revistas.unc.edu.ar/index.php/med/article/view/34867 |
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I10-R10-article-348672022-06-07T14:43:30Z Respiratory infection with human bocavirus 1. Report of a case of viral pneumonia in an infant without comorbidity Infección respiratoria por bocavirus humano 1. Reporte de un caso de neumonía viral en lactante sin comorbilidades previas A Boggio , GA Montañez Sandoz , A Abbiatti , G Musacchio , NN Provenzani , LM Salvetti , MB Adamo , MP Moreno , LB Human Bocavirus-1 infant pneumonia lower respiratory tract infections Bocavirus Humano 1 lactante neumonía infección respiratoria aguda baja . Abstract: Human Bocavirus-1/HBoV1 causes acute respiratory infections/ARI (bronchiolitis/pneumonia) mostly in young children. It was identified in 2005 and has not yet been incorporated into the routine virus screening in ARI. Symptoms of viral pneumonia in children less than 2 years old are often interpreted as of bacterial etiology, leading to unnecessary administration of antibiotics. Objective: to report the case of a previously healthy infant who developed HBoV1 pneumonia without complications, in order to consider HBoV1 as one of the possible agents involved. Clinical case. 19-month-old female, full-term/2780 grams. No relevant personal or familiar pathological history; complete vaccination. Reason for consultation: fever, cough, and shortness of breath. Antecedents: 3 days before, she started with rhinitis and dry cough. She had a fever peak of 38.7°C, so her pediatrician prescribed oral amoxicillin. On Apr/26/2021 she went to the emergency service due to persistent fever and worsening cough. Mild/moderate respiratory distress was observed; inhaled adrenergic drugs were administered, with good clinical response and outpatient follow-up (prior swabbing for COVID-19). The next day, she returned with food rejection and was hospitalized. Laboratory: hemoglobin 10.9g/dl, hematocrit 34%; leukocytes: 15,380 (69/15/15); platelets 299,000/ml; gases: 7.48/27.2/84.2/19.9/-2.1); ionogram Na 134/K 4/Cl 100; CRP: 17.8. Chest X-ray compatible with viral pneumonia. O2 saturation: 93%. Amoxicillin was suspended; hydration, oxygen by nasal cannula (3 liters/min) and inhaled salbutamol were administered. The complete panel of respiratory viruses was negative (RSV, Parainfluenza 1-3, Metapneumovirus, Influenza A/B and Adenovirus by IF; PCR for COVID-19: negative). HBoV1 detected in nasal secretions and serum (PCR with high viral load/>1x106 c.gen/mL) was the only positive finding. Evolution: 48 hours after admission she was afebrile; O2 saturation 95%; supplementary oxygen therapy was suspended. Patient was discharged without complications. In the follow-up (10 days) she did not show relapses or respiratory symptoms, so aerosol therapy was suspended. Conclusions. A case of HBoV1 infection in an infant with no comorbidity is reported. Recognition of the viral etiology in hospitalized cases of pneumonia contributes to optimize the clinical management of patients with rational use of antibiotics. HBoV1 should be included in the standard screening for respiratory infections in hospitalized infants. Resumen: Bocavirus humano-1/HBoV1 es un parvovirus que causa infecciones respiratorias/IRA (bronquiolitis o neumonía) sobre todo en niños pequeños. Fue identificado en 2005 y aún no está incorporado a la pesquisa de virus habituales en IRA. Los cuadros de neumonía viral en menores de 2 años suelen interpretarse como de etiología bacteriana, administrándoles antibióticos innecesariamente. Objetivo: Reportar el caso de una lactante, sin comorbilidades previas, que desarrolla neumonía por HBoV1 sin complicaciones, a fin de considerar a este virus como uno más de los posibles agentes involucrados. Caso clínico. Paciente femenina de 19 meses de edad, nacida a término/2780gramos. Sin antecedentes patológicos, ni familiares relevantes; vacunación completa. MC: fiebre, tos y dificultad respiratoria. Antecedentes: 3 días previos inicia con rinitis y tos seca. Presenta un pico febril de 38,7°C por lo que su pediatra prescribió amoxicilina vía oral. El día 26/04/2021 concurre al servicio de emergencia por persistencia de la fiebre y empeoramiento de la tos. Se objetiva dificultad respiratoria leve/moderada; se administra adrenérgicos inhalados, con buena repuesta clínica y seguimiento ambulatorio (previo hisopado para COVID-19). Al día siguiente, ante el rechazo alimentario se decide internación. Laboratorio: Hemoglobina 10.9g/dl-Hto 34%; GB:15.380(69/15/15); plaquetas 299.000/ml; Gases:7.48/27.2/84.2/19.9/-2.1); Ionograma (Na134/K4/Cl100); PCR:17.8. Rx tórax compatible con neumonía viral. SatO2:93%. Se suspende amoxicilina, se administra hidratación, oxígeno por naricera-3litros/min y salbutamol inhalado. El panel completo de virus respiratorios resultó negativo (IFI para VRS, Parainfluenza 1,2,3, Metapneumovirus, Infuenza A y B y Adenovirus; PCR para COVID-19: negativo). Detección de HBoV1 en secreciones nasales y suero (PCR positiva con alta carga viral/>1x10^6c.gen/mL) fue el único hallazgo positivo. Evolución: a las 48 hs. del ingreso estaba afebril; Sat 95%; se suspende oxigenoterapia. Alta sin complicaciones. El seguimiento (hasta 10 días) no mostró recaídas o sintomatología respiratoria por lo que se suspende aerosolterapia. Conclusiones. Se reporta un caso de infección por BoVH1 en lactante sin comorbilidad previa. El reconocimiento de la etiología viral en los cuadros hospitalizados por neumonía contribuye a optimizar el manejo clínico de estos pacientes con uso más racional de antibióticos. La detección de BoVH1 debería ser parte de la pesquisa estándar para infecciones respiratorias en lactantes hospitalizados . Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2021-10-12 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion texto texto texto https://revistas.unc.edu.ar/index.php/med/article/view/34867 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 78 No. Suplemento (2021): Suplemento JIC XXII Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 78 Núm. Suplemento (2021): Suplemento JIC XXII Revista da Faculdade de Ciências Médicas de Córdoba; v. 78 n. Suplemento (2021): Suplemento JIC XXII 1853-0605 0014-6722 http://creativecommons.org/licenses/by-nc/4.0 |