Predictors of weaning and mortality in prolonged mechanical ventilation-Surviving survival

Objectives: to describe a sample of tracheostomized patients requiring prolonged mechanical ventilation who were admitted to a weaning center, to analyze their evolution and to determine the predictors of weaning failure from mechanical ventilation and of mortality. Design: an observational and retr...

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Detalles Bibliográficos
Autores principales: Hannun , Marcos, Villalba, Dario, Díaz Ballve , Ladislao, Matesa , Amelia, Pedace , Paula, Tocalini, Pablo, Pérez Calvo, Eliana, Scrigna , Mariana, Collins , Jessica, Areas , Laura, Gil Rossetti , Gregorio, Planells , Fernando
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2022
Materias:
respiration, artificial
intensive care units
mortality
ventilator weaning
rehabilitation centers
respiración artificial
unidades de cuidados intensivos
mortalidad
desconexión del ventilador
centros de rehabilitación
respiração artificial
unidades de terapia intensiva
mortalidade
desmame do respirador
centros de reabilitação
Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/33184
Aporte de:
Revistas de la UNC de Universidad Nacional de Córdoba
Descripción
Sumario:Objectives: to describe a sample of tracheostomized patients requiring prolonged mechanical ventilation who were admitted to a weaning center, to analyze their evolution and to determine the predictors of weaning failure from mechanical ventilation and of mortality. Design: an observational and retrospective cohort study was carried out, in the period between January 2005 and December 2017. Setting: weaning and rehabilitation center Patients: all tracheostomized patients requiring mechanical ventilation who were admitted during the study period were included. Of 1027 patients admitted to the respiratory care service, a consecutive sample of 677 patients was analyzed. Main variables of interest: the main variables were mortality and weaning failure from mechanical ventilation. Results: age older than 70 years (OR 1,461 95% CI 1,016-2,099), a cardiovascular history (OR 1,533 95% CI 1,050-2,237), admission due to respiratory disease (OR 1,538 95% CI 1,001-2,364) and presenting more than 105 days of hospitalization (OR 0.408 95% CI 0.261-0.637) were found as predictors of weaning failure. The predictors of mortality were, age over 70 years (OR 2,116 95% CI 1,491-3,004), history of cerebrovascular accident (OR 1,991 95% CI 1,255-3,158), admission to intensive care due to cardiorespiratory arrest (OR 5,821 95% CI 2,193-15,445) and presenting more than 64 days of hospitalization (OR1.63 95% CI 1,116-2,292). Conclusion: The data found in this study manage to describe factors associated with weaning and mortality of patients in a weaning and rehabilitation center.

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