26 year-old male patient with bone marrow trasplantation

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26 year-old male patient with diagnosis of acute lymphoblastic leukemia in 2006, who underwent chemotherapy and suffered a relapse and pulmonary aspergillosis as a complication. In 2009, he received bone marrow transplant. After it, he developed cutaneous and intestinal graft versus host disease (GV...

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Autor principal: Bürgesser, María Virginia
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2011
Materias:
rasplante
quimioterapia
leucemia
aspergilosis
daño alveolar difuso
transplant
chemotherapy
leukemia
aspergillosis
diffuse alveolar damage
Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/22563
Aporte de:
Revistas de la UNC de Universidad Nacional de Córdoba
id I10-R10-article-22563
record_format ojs
spelling I10-R10-article-225632019-05-20T10:48:56Z 26 year-old male patient with bone marrow trasplantation Paciente de 26 años trasplantado de Médula Ósea Bürgesser, María Virginia rasplante quimioterapia leucemia aspergilosis daño alveolar difuso transplant chemotherapy leukemia aspergillosis diffuse alveolar damage 26 year-old male patient with diagnosis of acute lymphoblastic leukemia in 2006, who underwent chemotherapy and suffered a relapse and pulmonary aspergillosis as a complication. In 2009, he received bone marrow transplant. After it, he developed cutaneous and intestinal graft versus host disease (GVH). He was admitted for diarrhea. Then he presented grade IV dyspnea, patchy alveolar infiltrates on chest computed tomography and pancytopenia with impaired renal function as laboratory findings. He entered Intensive Care Unit, dying 7 days later. The oncologist who discussed the case defined this patient as a high risk case because of type of transplant received, relapse and complications. His diagnostic hypotheses were: CMV infection, pulmonary aspergillosis reactivation, chronic GVH, Pneumocystis jiroveci infection, mycobacteriosis and pseudomembranous colitis. Parcial autopsy revealed diffuse intra-alveolar hemorrhage, diffuse alveolar damage, right pulmonary infarction with microthrombosis and bronchiolitis obliterans organizing pneumonia. Paciente de 26 años trasplantado de médula ósea. Reporte de autopsia parcialPaciente de sexo masculino de 26 años con diagnóstico de leucemia linfoblástica aguda en 2006, tratado con quimioterapia, sufriendo una recaída y aspergilosis pulmonar como complicación. En 2009 recibe trasplante de médula ósea con desarrollo de enfermedad injerto versus huésped (GVH) cutánea e intestinal. Es internado por diarrea. Luego presenta disnea grado IV, infiltrados alveolares en parches en tomografía de tórax y pancitopenia con alteración de la función renal en el laboratorio. Pasa a Unidad de Cuidados Intensivos y fallece a los 7 días. El oncólogo que discutió el caso definió al paciente como de alto riesgo por el tipo de trasplante recibido, la recaída y las complicaciones. Sus hipótesis con respecto al cuadro fueron: infección por CMV, reactivación de aspergilosis pulmonar, desarrollo de GVH crónica, infección por Pneumocystis jiroveci o micobacterias y colitis pseudomembranosa. La anatomía patológica reveló hemorragia intraalveolar difusa, daño alveolar difuso, infarto pulmonar derecho con microtrombosis y bronquiolitis obliterante con neumonía organizante.Palabras claves: trasplante, quimioterapia, leucemia, aspergilosis, daño alveolar difuso. Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2011-02-06 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.unc.edu.ar/index.php/med/article/view/22563 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 68 No. 1 (2011); 33-38 Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 68 Núm. 1 (2011); 33-38 Revista da Faculdade de Ciências Médicas de Córdoba; v. 68 n. 1 (2011); 33-38 1853-0605 0014-6722 10.31053/1853.0605.v68.n1 spa https://revistas.unc.edu.ar/index.php/med/article/view/22563/22183 Derechos de autor 2018 Universidad Nacional de Córdoba
institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-10
container_title_str Revistas de la UNC
language Español
format Artículo revista
topic rasplante
quimioterapia
leucemia
aspergilosis
daño alveolar difuso
transplant
chemotherapy
leukemia
aspergillosis
diffuse alveolar damage
spellingShingle rasplante
quimioterapia
leucemia
aspergilosis
daño alveolar difuso
transplant
chemotherapy
leukemia
aspergillosis
diffuse alveolar damage
Bürgesser, María Virginia
26 year-old male patient with bone marrow trasplantation
topic_facet rasplante
quimioterapia
leucemia
aspergilosis
daño alveolar difuso
transplant
chemotherapy
leukemia
aspergillosis
diffuse alveolar damage
author Bürgesser, María Virginia
author_facet Bürgesser, María Virginia
author_sort Bürgesser, María Virginia
title 26 year-old male patient with bone marrow trasplantation
title_short 26 year-old male patient with bone marrow trasplantation
title_full 26 year-old male patient with bone marrow trasplantation
title_fullStr 26 year-old male patient with bone marrow trasplantation
title_full_unstemmed 26 year-old male patient with bone marrow trasplantation
title_sort 26 year-old male patient with bone marrow trasplantation
description 26 year-old male patient with diagnosis of acute lymphoblastic leukemia in 2006, who underwent chemotherapy and suffered a relapse and pulmonary aspergillosis as a complication. In 2009, he received bone marrow transplant. After it, he developed cutaneous and intestinal graft versus host disease (GVH). He was admitted for diarrhea. Then he presented grade IV dyspnea, patchy alveolar infiltrates on chest computed tomography and pancytopenia with impaired renal function as laboratory findings. He entered Intensive Care Unit, dying 7 days later. The oncologist who discussed the case defined this patient as a high risk case because of type of transplant received, relapse and complications. His diagnostic hypotheses were: CMV infection, pulmonary aspergillosis reactivation, chronic GVH, Pneumocystis jiroveci infection, mycobacteriosis and pseudomembranous colitis. Parcial autopsy revealed diffuse intra-alveolar hemorrhage, diffuse alveolar damage, right pulmonary infarction with microthrombosis and bronchiolitis obliterans organizing pneumonia.
publisher Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
publishDate 2011
url https://revistas.unc.edu.ar/index.php/med/article/view/22563
work_keys_str_mv AT burgessermariavirginia 26yearoldmalepatientwithbonemarrowtrasplantation
AT burgessermariavirginia pacientede26anostrasplantadodemedulaosea
first_indexed 2022-08-20T01:26:12Z
last_indexed 2022-08-20T01:26:12Z
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