A mouse attenuated mutant of Junin virus with an altered envelope glycoprotein

The XJCl3 strain of Junin virus (JV) and the mouse-attenuated mutant Cl67 showed different GP 38 peptide mapping after limited proteolysis with ficin and papain; viral infectivity of both viruses also exhibited a different susceptibility to protease treatment. A correlation between envelope glycopro...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autor principal: Scolaro, L.A
Otros Autores: Mersich, S.E, Damonte, E.B
Formato: Capítulo de libro
Lenguaje:Inglés
Publicado: Springer-Verlag 1990
Acceso en línea:Registro en Scopus
DOI
Handle
Registro en la Biblioteca Digital
Aporte de:Registro referencial: Solicitar el recurso aquí
Descripción
Sumario:The XJCl3 strain of Junin virus (JV) and the mouse-attenuated mutant Cl67 showed different GP 38 peptide mapping after limited proteolysis with ficin and papain; viral infectivity of both viruses also exhibited a different susceptibility to protease treatment. A correlation between envelope glycoprotein alteration and JV virulence in neonatal mice is proposed. © 1990 Springer-Verlag.
Bibliografía:Auperin, D.D., McCormick, J.B., Nucleotide sequence of the Lassa virus (Josiah strain) S genome RNA and amino acid sequence comparison of the N and GPC proteins to other arenaviruses (1989) Virology, 168, pp. 421-425
Bruns, M., Lehmann-Grube, F., Lymphocytic choriomeningitis virus. VII. Structural alterations of the virion by treatment with proteolytic enzymes without loss of infectivity (1984) J Gen Virol, 65, pp. 1431-1435
Cleveland, D.W., Fischer, S.G., Kirschner, M.W., Laemmli, U.K., Peptide mapping by limited proteolysis in sodium-dodecyl sulfate and analysis by gel electrophoresis (1977) J Biol Chem, 252, pp. 1103-1106
Cordonnier, A., Montagnier, L., Emerman, M., Single amino acid changes in HIV envelope affect viral tropism and receptor binding (1989) Nature, 340, pp. 571-574
Cresta, B., Padula, P., Martínez Segovia, Z.M., Biological properties of Junin virus proteins (1980) Intervirology, 13, pp. 284-288
Damonte, E.B., Mersich, S.E., Candurra, N.A., Coto, C.E., Cross-reactivity between Junin and Tacaribe viruses as determined by neutralization and immunoprecipitation (1986) Med Microbiol Immunol, 175, pp. 85-88
Davis, N.L., Fuller, F.J., Dougherty, W.G., Olted, R.A., Johnston, R.E., A single nucleotide change in the E2 glycoprotein of Sindbis virus affects penetration rate in cell culture and virulence in neonatal mice (1986) Proc Natl Acad Sci USA, 83, pp. 6771-6775
De Mitri, M.I., Martínez Segovia, Z.M., Polypeptide synthesis in Junin virus infected BHK-21 cells (1985) Acta Virol, 29, pp. 97-103
Grau, O., Franze-Fernandez, M.T., Romanowski, V., Rustici, S.M., Rosas, M.F., Junin virus structure (1981) The replication of negative strand viruses, pp. 11-14. , D.H.L., Bishop, R.W., Compans, Elsevier, Amsterdam
Johnson, B.J.B., Kinney, R.M., Kost, C.L., Trent, D.W., Molecular determinants of Alphavirus neurovirulence: nucleotide and deduced protein sequence changes during attenuation of Venezuelan equine encephalitis virus (1986) J Gen Virol, 67, pp. 1951-1960
Mersich, S.E., Castilla, V., Damonte, E.B., Lectin affinity of Junin virus glycoproteins (1988) Ann Inst Pasteur Virol, 139, pp. 277-284
Scolaro, L.A., Mersich, S.E., Damonte, E.B., Atenuación en virulencia para ratón lactante de una mutante de virus Junín (1987) Rev Arg Microbiol, 19, pp. 9-17
Scolaro, L.A., Mersich, S.E., Damonte, E.B., Reduced virulence of a Junin virus mutant is associated with restricted multiplication in murine cells (1989) Virus Res, 13, pp. 283-294
Weissenbacher, M.C., Laguens, R.P., Coto, C.E., Argentine hemorrhagic fever (1987) Curr Top Microbiol Immunol, 134, pp. 79-116
ISSN:03048608
DOI:10.1007/BF01311059