Prostate cancer cell-stromal cell crosstalk via FGFR1 mediates antitumor activity of dovitinib in bone metastases
Bone is the most common site of prostate cancer (PCa) progression to a therapy-resistant, lethal phenotype. We found that blockade of fibroblast growth factor receptors (FGFRs) with the receptor tyrosine kinase inhibitor dovitinib has clinical activity in a subset of men with castration-resistant PC...
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| Autor principal: | Wan, X. |
|---|---|
| Otros Autores: | Corn, P.G, Yang, J., Palanisamy, N., Starbuck, M.W, Efstathiou, E., Li-Ning Tapia, E.M, Zurita, A.J, Aparicio, A., Ravoori, M.K, Vazquez, E.S, Robinson, D.R, Wu, Y.-M, Cao, X., Iyer, M.K, McKeehan, W., Kundra, V., Wang, F., Troncoso, P., Chinnaiyan, A.M, Logothetis, C.J, Navone, N.M |
| Formato: | Capítulo de libro |
| Lenguaje: | Inglés |
| Publicado: |
American Association for the Advancement of Science
2014
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| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
| Aporte de: | Registro referencial: Solicitar el recurso aquí |
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