Prostate cancer cell-stromal cell crosstalk via FGFR1 mediates antitumor activity of dovitinib in bone metastases
Bone is the most common site of prostate cancer (PCa) progression to a therapy-resistant, lethal phenotype. We found that blockade of fibroblast growth factor receptors (FGFRs) with the receptor tyrosine kinase inhibitor dovitinib has clinical activity in a subset of men with castration-resistant PC...
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Otros Autores: | , , , , , , , , , , , , , , , , , , , , |
Formato: | Capítulo de libro |
Lenguaje: | Inglés |
Publicado: |
American Association for the Advancement of Science
2014
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Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
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