Lipase-catalyzed synthesis of substituted phenylacetamides: Hammett analysis and computational study of the enzymatic aminolysis

A series of hydroxy-, methoxy-, and nitrophenylacetamides was synthesized by enzyme catalysis. The 28 new products were obtained through a lipase-catalyzed two-step reaction in very good to excellent yield. In the case of nitro derivatives, a one-pot, two-step methodology allowed the desired product...

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Autor principal: García Liñares, G.
Otros Autores: Arroyo Mañez, P., Baldessari, A.
Formato: Capítulo de libro
Lenguaje:Inglés
Publicado: Wiley-VCH Verlag 2014
Acceso en línea:Registro en Scopus
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