Glycoprotein-mediated biological properties of a host range mutant of Junin virus
The biological properties mediated by the main envelope glycoprotein (GP1) of a mouse-attenuated mutant of Junin virus, named Cl67, were investigated in comparison with its parental strain XJCl3. In contrast to the parental strain, this mutant was unable to multiply in primary cultures of mouse embr...
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Elsevier Masson SAS
1997
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| LEADER | 06534caa a22007577a 4500 | ||
|---|---|---|---|
| 001 | PAPER-20111 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518205130.0 | ||
| 008 | 190411s1997 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-0030660626 | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a RESVE | ||
| 100 | 1 | |a Scolaro, L.A. | |
| 245 | 1 | 0 | |a Glycoprotein-mediated biological properties of a host range mutant of Junin virus |
| 260 | |b Elsevier Masson SAS |c 1997 | ||
| 270 | 1 | 0 | |m Scolaro, L.A.; Departamento de Quimica Biologica, Fac. Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, 1428 Buenos Aires, Argentina |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Burns, J.W., Buchmeier, M.J., Glycoproteins of the arenaviruses (1993) The Arenaviridae, pp. 17-35. , Salvato M.S., ed. Plenum Press, New York | ||
| 504 | |a Candurra, N.A., Damonte, E.B., Coto, C.E., Antigenic relationships between attenuated and pathogenic strains of Junin virus (1989) J. Med. Virol., 27, pp. 145-150 | ||
| 504 | |a Castilla, V., Mersich, S.E., Low pH-induced fusion of vero cells infected with Junin virus (1996) Arch. Virol., 141, pp. 1307-1317 | ||
| 504 | |a Cresta, B., Padula, P., Martínez Segovia, Z., Biological properties of Junin virus proteins. - I. Identification of the immunogenic glycoprotein (1980) Intervirology, 13, pp. 284-288 | ||
| 504 | |a Di Simone, C., Buchmeier, M.J., Kinetics and pH dependence of acid-induced structural changes in the lymphocytic Choriomeningitis Virus glycoprotein complex (1995) Virology, 209, pp. 3-9 | ||
| 504 | |a Dimmock, N., Update on the neutralisation of animal viruses (1995) Rev. Med. Virol., 5, pp. 165-179 | ||
| 504 | |a Mersich, S.E., Castilla, V., Damonte, E.B., Lectin affinity of Junin virus glycoproteins (1988) Ann. Inst. Pasteur/Virol., 139, pp. 277-284 | ||
| 504 | |a Nakamura, G., Byrn, R., Wilkes, D., Fox, J.A., Hobbs, M.R., Hastings, R., Wessling, H.C., Berman, P.W., Strain specificity and binding affinity requirements of neutralizing antibodies to the C4 domain of gp120 from human immunodeficiency virus type 1 (1993) J. Virol., 67, pp. 6179-6191 | ||
| 504 | |a Sánchez, A., Pifat, D.Y., Kenyon, R.H., Peters, C.J., McCormick, J.B., Kiley, M.P., Junin virus monoclonal antibodies: Characterization aind cross reactivity with other arenaviruses (1989) J. Gen. Virol., 70, pp. 1125-1132 | ||
| 504 | |a Scolaro, L.A., Mersich, S.E., Damonte, E.B., Reduced virulence of a Junin virus mutant is associated with restricted multiplication in murine cells (1989) Virus Res., 13, pp. 283-294 | ||
| 504 | |a Scolaro, L.A., Mersich, S.E., Damonte, E.B., A mouse attenuated mutant of Junin virus with an altered envelope glycoprotein (1990) Arch. Virol., 111, pp. 257-262 | ||
| 504 | |a Scolaro, L.A., Mersich, S.E., Damonte, E.B., Experimental infection of suckling mice with a host range mutant of Junin virus (1991) J. Med Virol., 34, pp. 237-240 | ||
| 504 | |a Silber, A.M., Candurra, N.A., Damonte, E.B., The effects of oligosaccharide trimming inhibitors on glycoprotein expression and infectivity of Junin virus (1993) FEMS Microbiol. Lett., 109, pp. 39-44 | ||
| 504 | |a Suomalainen, M., Liljeström, P., Garoff, H., Spike protein-nucleocapsid interactions drive the budding of alphaviruses (1992) J. Virol., 66, pp. 4737-4747 | ||
| 504 | |a Villarete, L., Somasundaram, T., Ahmed, R., Tissue-mediated selection of viral variants: Correlation between glycoprotein mutation and growth :In neuronal cells (1994) J. Virol., 68, pp. 7490-7496 | ||
| 504 | |a Wiley, D.C., Skehel, J.J., Viral membranes (1991) Fundamental Virology, pp. 63-85. , Fields, B.N. & Knipe, D.M., ed. Raven Press, New York | ||
| 520 | 3 | |a The biological properties mediated by the main envelope glycoprotein (GP1) of a mouse-attenuated mutant of Junin virus, named Cl67, were investigated in comparison with its parental strain XJCl3. In contrast to the parental strain, this mutant was unable to multiply in primary cultures of mouse embryo fibroblasts (MEFs). Impairment of Cl67 multiplication was associated with a lack of virus binding to MEF, probably due to an altered interaction between GP1 and cellular receptors. Antigenic and immunogenic characterization of GP1, performed by neutralization assays, demonstrated that, under certain conditions, polyclonal and monoclonal antibodies exhibited differential affinity and specificity for each virus. Cl67-infected Vero cells showed a marked pH-dependent fusion capability, suggesting more efficient tow pH triggering of fusion by mutant virus GP1 In comparison with the parental strain. |l eng | |
| 536 | |a Detalles de la financiación: Universidad de Buenos Aires | ||
| 536 | |a Detalles de la financiación: Universidad de Buenos Aires | ||
| 536 | |a Detalles de la financiación: This work was supported by Fundaci6n Antorchas, Universidad de Buenos Aires (UBA) and Consejo National de Investigeciones Cientificas y Tecnol6gicas (CONICET). E.B.D. and L.A.S are members of the Research Career of CONICET. | ||
| 593 | |a Laboratorio de Virología, Depto. de Quim. Biol., Ciudad Universitaria, 1428 Buenos Aires, Argentina | ||
| 690 | 1 | 0 | |a ANTIGENICITY |
| 690 | 1 | 0 | |a ATTENUATION |
| 690 | 1 | 0 | |a BINDING |
| 690 | 1 | 0 | |a GLYCOPROTEIN |
| 690 | 1 | 0 | |a GP1 |
| 690 | 1 | 0 | |a HOST-RANGE MUTANT |
| 690 | 1 | 0 | |a JUNIN VIRUS |
| 690 | 1 | 0 | |a GLYCOPROTEIN |
| 690 | 1 | 0 | |a ANTIGENICITY |
| 690 | 1 | 0 | |a ARTICLE |
| 690 | 1 | 0 | |a CONTROLLED STUDY |
| 690 | 1 | 0 | |a JUNIN VIRUS |
| 690 | 1 | 0 | |a NONHUMAN |
| 690 | 1 | 0 | |a PRIORITY JOURNAL |
| 690 | 1 | 0 | |a PROTEIN ANALYSIS |
| 690 | 1 | 0 | |a VERO CELL |
| 690 | 1 | 0 | |a VIRUS MUTANT |
| 690 | 1 | 0 | |a JUNIN VIRUS |
| 650 | 1 | 7 | |2 spines |a FUSION |
| 700 | 1 | |a Damonte, E.B. | |
| 773 | 0 | |d Elsevier Masson SAS, 1997 |g v. 148 |h pp. 323-331 |k n. 5 |p RES. VIROL. |x 09232516 |t Research in Virology | |
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| 856 | 4 | 0 | |u https://doi.org/10.1016/S0923-2516(97)89128-5 |y DOI |
| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_09232516_v148_n5_p323_Scolaro |y Handle |
| 856 | 4 | 0 | |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09232516_v148_n5_p323_Scolaro |y Registro en la Biblioteca Digital |
| 961 | |a paper_09232516_v148_n5_p323_Scolaro |b paper |c PE | ||
| 962 | |a info:eu-repo/semantics/article |a info:ar-repo/semantics/artículo |b info:eu-repo/semantics/publishedVersion | ||
| 999 | |c 81064 | ||