Simulation of the neutron flux in the irradiation facility at RA-3 reactor

A facility for the irradiation of a section of patients' explanted liver and lung was constructed at RA-3 reactor, Comisión Nacional de Energía Atómica, Argentina. The facility, located in the thermal column, is characterized by the possibility to insert and extract samples without the need to...

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Detalles Bibliográficos
Autor principal: Bortolussi, S.
Otros Autores: Pinto, J.M, Thorp, S.I, Farias, R.O, Soto, M.S, Sztejnberg, M., Pozzi, E.C.C, Gonzalez, S.J, Gadan, M.A, Bellino, A.N, Quintana, J., Altieri, S., Miller, M.
Formato: Capítulo de libro
Lenguaje:Inglés
Publicado: 2011
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Acceso en línea:Registro en Scopus
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Sumario:A facility for the irradiation of a section of patients' explanted liver and lung was constructed at RA-3 reactor, Comisión Nacional de Energía Atómica, Argentina. The facility, located in the thermal column, is characterized by the possibility to insert and extract samples without the need to shutdown the reactor. In order to reach the best levels of security and efficacy of the treatment, it is necessary to perform an accurate dosimetry. The possibility to simulate neutron flux and absorbed dose in the explanted organs, together with the experimental dosimetry, allows setting more precise and effective treatment plans. To this end, a computational model of the entire reactor was set-up, and the simulations were validated with the experimental measurements performed in the facility. © 2011 Elsevier Ltd.
Bibliografía:Miller, M., Quintana, J., Ojeda, J., Langan, S., Thorp, S., Pozzi, E., Sztejnberg, M., Graiño, F., New irradiation facility for biomedical applications at the RA-3 reactor thermal column. (2008), pp. 379-382. , In: Proceedings of the 13th ICNCT; Miller, M.E., Mariani, L.E., Sztejnberg Gonçalves Carralves, M.L., Skumanic, M., Thorp, S.I., Implantable self-powered detector for on-line determination of neutron flux in patients during NCT treatment (2004) Appl. Radiat. Isot., 61 (5), pp. 1033-1037
Soto, M.S., González, S.J., Thorp, S.I., Pozzi, E.C.C., Farías, R.O., Gadan, M.A., Miller, M.E., Characterization and optimization of the RA-3 preliminary dosimetry for the radiotolerance study of the normal sheep lung. (2009), In: Proceedings of the Young Researchers Boron Neutron Capture Therapy Meeting, Mainz, Germany; (2005), 1-2. , X-5 Monte Carlo Team, MCNP-a general Monte Carlo N-Particle transport code, version 5, LA-UR-031987, LA-CP-03-0245, and LA-CP-03-0284, Los Alamos National Laboratory, New Mexico, USA; Zonta, A., Pinelli, T., Prati, U., Roveda, L., Ferrari, C., Clerici, A.M., Zonta, C., Fossati, F., Extra-corporeal liver BNCT for the treatment of diffuse metastases: what was learned and what is still to be learned (2009) Appl. Radiat. Isot., 67, pp. 67-70
ISSN:09698043
DOI:10.1016/j.apradiso.2011.03.034