Anticoagulant Activity of a Unique Sulfated Pyranosic (133) - ß - L - Arabinan through Direct Interaction with Thrombin

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Background: Many seaweed polysaccharides have anticoagulant activity, but the mechanism of action was elucidated in a few cases. Results: A highly sulfated pyranosic ß-arabinan exerts its activity through direct and indirect inhibition of thrombin. Conclusion: The structure and mechanism of action o...

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Detalles Bibliográficos
Otros Autores: Fernández, Paula Virginia, Quintana, Irene, Cerezo, Alberto S., Caramelo, Julio J., Pol Fachin, Laercio, Verli, Hugo, Estévez, José Manuel, Ciancia, Marina
Formato: Artículo
Lenguaje:Inglés
Materias:
ANTICOAGULANT ACTIVITIES
AMINO ACID RESIDUES
ARABINANS
SULFATED POLYSACCHARIDES
Acceso en línea:http://ri.agro.uba.ar/files/download/articulo/2013fernandez.pdf
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Biblioteca Central (FAUBA) de Universidad de Buenos Aires
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