The cyclophilin ROC1 links phytochrome and cryptochrome to brassinosteroid sensitivity

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Although multiple photoreceptors converge to control common aspects of seedling de-etiolation, we are relatively ignorant of the genes acting at or downstream of their signalling convergence. To address this issue we screened for mutants under a mixture of blue plus far-red light and identified roc1...

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Detalles Bibliográficos
Autor principal: Trupkin, Santiago Ariel
Otros Autores: Mora García, Santiago, Casal, Jorge José
Formato: Artículo
Lenguaje:Inglés
Materias:
ARABIDOPSIS
BRASSINOSTEROID
CRYPTOCHROME
PHYTOCHROME
ROTAMASE CYCLOPHILIN 1
BRASSINOSTEROIDS
CRYPTOCHROMES
CYCLOPHILIN
PHOSPHORYLATION
PLANTS [BOTANY]
TRANSCRIPTION FACTORS
GENES
ARABIDOPSIS PROTEIN
BES1 PROTEIN, ARABIDOPSIS
CRY1 PROTEIN, ARABIDOPSIS
NUCLEAR PROTEIN
PHYTOCHROME A
ROC1 PROTEIN, ARABIDOPSIS
GENETICS
LIGHT
METABOLISM
MUTATION
PHENOTYPE
ARABIDOPSIS PROTEINS
NUCLEAR PROTEINS
Acceso en línea:http://ri.agro.uba.ar/files/intranet/articulo/2012Trupkin.pdf
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Biblioteca Central (FAUBA) de Universidad de Buenos Aires
Descripción
Sumario:Although multiple photoreceptors converge to control common aspects of seedling de-etiolation, we are relatively ignorant of the genes acting at or downstream of their signalling convergence. To address this issue we screened for mutants under a mixture of blue plus far-red light and identified roc1-1D. The roc1-1D mutant, showing elevated expression of the ROTAMASE CYCLOPHILIN 1 [ROC1/AtCYP18-3] gene, and partial loss-of function roc1 alleles, has defects in phytochrome A [phyA]-, cryptochrome 1 [cry1]- and phytochrome B [phyB]-mediated de-etiolation, including long hypocotyls under blue or far-red light. These mutants show elevated sensitivity to brassinosteroids in the light but not in the dark. Mutations at brassinosteroid signalling genes and the application of a brassinosteroid synthesis inhibitor eliminated the roc1 and roc1-D phenotypes. The roc1 and roc1-D mutants show altered patterns of phosphorylation of the transcription factor BES1, a known point of control of sensitivity to brassinosteroids, which correlate with the expression levels of genes directly targeted by BES1. We propose a model where perception of light by phyA, cry1 or phyB activates ROC1 [at least in part by enhancing its expression]. This in turn reduces the intensity of brassinosteroid signalling and fine-tunes seedling de-etiolation.
ISSN:1365-313X (en línea)
0960-7412 (impreso)

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