Developmental Biology /

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Detalles Bibliográficos
Autor principal: Scott, Gilbert F.
Formato: Libro
Lenguaje:Inglés
Publicado: Sunderland : Sinauer Associates , 1997
Edición:5a. ed. ;
Materias:
Aporte de:Registro referencial: Solicitar el recurso aquí
Tabla de Contenidos:
  • Part I: An introductioon to developmental biology. An introduction to animal development- The scope of deelopmenta biology
  • The problems of developmental biology
  • The stages of animal development
  • Our eukaryotic heritage--Development among the unicellular eukaryotes: control of developmental morphogeneis in acetabularia
  • Differentiation in the amoeboflaellate naegleria-- The origins of sexual reproduction. olonial eukaryotes: the evolution of differention. The volvocaceans: Sideliht and speculations: sex and individuality in volvox: Differentiation and morphogenesis in dictyostelium. Sidelights and speculations: evidence and antibodies
  • Sdelihts and speculations: How the grex knows whitch end is up: developmetal patterns among the metazoans. The porifera. Protomes and deuterostomes
  • 2. Genes and development: introduction and techniques. The embryological origins of the gene theory. Nucleus or cytoplasm: which controls heredy?
  • The Xchromosome as bridge between genes and development. The split between embryology and genetic early attempts at developmental genetics. Early attempts at developmental genetics. Evidence for genomic equivalence: Metaplasia. Amphibian cloning: the pluripotency os somatic cells-- Sidelights and speculations: loning mammals for fun and profit of E. Coli and elephants: the operon model differential RNA synthesis. Cloning from genomic DNA. DNA hybridization: whithin and across species. DNA. sequencing. Analyzing mRNA through cDNA libraries. NRA localization techniques. In situ hybridization. Northern Blots--Finding rare messages by the polymerase chain reaction- Determining the function of a gene: transgenic cells and organisms. Techniques of inserting New NA Into a Cell Chimeric Mic. Gene-Targeting ("knockout") experiments. Determining the function of message: antisense RNA. Reinvestigation of old problem whith new methods. A conclusion and a caveat.-
  • 3. The cellular basis of morphogeneis: differential cell affinity. Differentil cell affinity: The thermodynamic Model of Cell Interantions
  • Siderights and Speculations: The molecular basis of cell Adhesion Molecular basis of cell-cell adhesions. The Classes of Cell Adhesion Molecules
  • Sidelightsand soeculations: Monoclonal Antibodies and Reverse Genetic. Cell aadhesion molecules-- Identify Cell Inmunoglobulin superfamily CANs. Cell junctional molecules: Gap junction proteins. The molecules basis of cell-substrate aaffinity-- The extracellular Matrix-- Cell Receptor molecules and signal transduction pathways-- The JAK-STAT Patway--The RTA-Ras Patway- Sideligths and Speculations: Dominant Negative Receptor Mutations
  • The inositol phosphate pahway
  • Cross-Talk Between Pathway- The Extracellular Matrix and Cell Surface as Sources of Developmentaly Critical Signals-- Reciprocal interactions at the cell surface.-
  • Part II: Patterns of development. Fertilization: beginning a new organism
  • Sperm
  • The egg-- Recognition of egg and perm: action at a distance
  • Sperm Attraction
  • Sperm Activation: the Acrosome reaction in Sea Urchisns. Sidelight and Speculationss: Action at a Distance: Mammalian Gametes. Recognition of egg and sperm: comtact of Gametes. Specie-Specific recognition in sea Urchins Gmete binding and Recognition in Mammals. Gamte fusion and the prevention of polyspemy- Fusion between Egg and Sperm Cell Membranes. Prvention of Polysperm. Sidelights and Speculations: the activation of gamte metabolism. Activation of egg metabolism. Early reposes. Late reponses. Fusion of the genetic material-- Sidelight and speculations: The nonequivalence of mammalian pronuclei. Rearrangement of egg cytoplasm- Preparation for cleavage.
  • Cleavage: creating multicellularity- Patterns of embryonic cleavage. Radial holoblastic cleavage-- The sea cucumber, synapta. Sea Urchins. Amphibians- Spiral holoblastic cleavage. Sidelights and speculations: Adaptation by modifying Embryonic Cleavage- Bilateral Holoblastic Cleavage- Rotational Holoblastic cleavage- Rotational holoblastic cleavage. Compaction-- Sidelights and Speculation: the cell surface and the mechanism of compaction-- Formation of the Inner Cell Mass. Scape from the zona pellucid-- Sidelights and Speculation: wins and embryonic stem cells. Meroblastic cleavage. Discoidal cleavage- Superficial cleavage--Sidelights and Speculation: Exceptions, generalizations anda parasitic wasp- Cleavage
  • Mechanisms of cleavage. Regulating the cleavage cycle- Muration-promoting factor- Sidelights and Speculation:MFP and Its Regulators- The cytoskeletal mechanisms of mitoso- The formation of new membranes.-
  • Gastrulation: reorganizing the embryonic cells. Sea urchin gastrulation- Ingression of primary mssenchyme
  • First stage of Archenteron Invagination
  • Second and third stages of Archenteron- Invagination- Gastrulation in fish-- The midblastula transition and the Acquisition of cell Motility-- Formation of germ layers
  • Amphibiangastrulation
  • Cell movements during Amphibian-- Gastrulation-- Positioning the blastopore-- Cel Movements and the Construction of the Archenteron-- Migration of the involuting mesoderm--Sidelights and Speculation: Molecular Regulators of development: ibronectin and the pathways form meodermal migration
  • Epiboly of the Ectoderm-- Gastrulation in birds-- Overview of avian Gastruation-- Mechanisma of Avian Gastrulation-- Gastrulation in mammals
  • Modifications for Development whithin Another Organism
  • Formation of extraembryonic Membranes.-
  • Early vertebrate development neurulation and the ectoderm-- Formation of the central Nervous system-- Neurulation: an overview-- Primary neurulation
  • The machincs of primary neurulation-- The formation of the Neural Plate-- Formation of the neural Plate-- Formation os the neural floor plate
  • The saping and bennding of the neural plate
  • Closure of the neural tube--Sidelights and Speculation:The dorsal-ventral patterning of the nervous system
  • Secondary neurulation
  • Differentiation of the neural tube-- Formation of brain regions
  • Sidelights and Speculation: Determining the forebrain and Midbrain regions
  • Tissue architecture of the cental nervous system
  • Cerebellar organization
  • Cerebral organization
  • Neuronal retina Differentiaion
  • The neural Cres
  • The neural crest and its derivatives - The trunk neural crest
  • Migration pathways of tunk neural crest cells
  • The extracellular Matrix and trunk neural crest maigration
  • Sidelights and Speculation:Analysis of mutations affeting neural crest cell development
  • The developmental potency of trunk neural crest cells
  • Final Differention of the Neural Crest cells
  • The Cephalic neural crest-- Migratory of the cephalic neural crest cells
  • Developmental potency of the cephalic Neural crest cells
  • The cardiac neural crest
  • The epidermis nd the origin of cutaneous structures
  • The origin of epiderma cells
  • Cutaneous Appendages
  • Axonal Specifity: The generation of neuonal diversity-- Vertebrate motor neuron specification
  • Motor neuron specification in Drosophila-- Pattern formation in the nervous system
  • Pathway selection: guidance by the extracellular matrix-- Guidance by the physical terrain: cntact guidance
  • Guidance by Adhesive gradients: haptotaxis
  • Guidance by Axon-specif migratory cues: the labeled pathways hypothesis
  • Guidance by specific growth cone repulsion
  • Sidelights and Speculation: Sex, smell and specific adhesion
  • Pathay selection: guidance by diffusible molecules
  • Multiple guidance cues
  • Vertebrate motor neurons
  • Retinal axons
  • Target selection
  • Adhesive specificities in different regions of the tectum
  • Address selection: activity-dependent development
  • Differential survival after innervation: neurotrophic factors-- Sidelights and Speculation:Fetal neurons in adulto hosts
  • the development of behaiors: constancy and plasticy
  • Early vertebrate development: mesoderm and endoderm
  • Mesoderm
  • Dorsal mesoderm: the notochord and the differentiation of somites
  • Paraxial mesoderm
  • Soitomeres and the initiation of somite formation
  • Generation of the somitic cell ypes myogenesis: differentiation of skeletal muscle
  • Sidelights and Speculation: Musle building and the MyoD Family of transcriional reguators
  • Osteogenesis: the develpment of bones
  • Sidelights and Speculation:Control of chondrogenesis at the growth plate
  • Lateral plate mesoderm
  • Formation of extraembryonic membranes
  • The heart
  • Formation of blood vessels
  • Sidelights and Speculation: Redirecting blood flow in the newborn mamml
  • The development of blood cells
  • The stem cell concept
  • Pluripotential stem cells and hematopoietic
  • Microenvironmente
  • Sites of hematopoiesis
  • Endoder
  • Pharynx
  • The digestive tube and its derivatives
  • Liver, pancreas and gallbladder-- The respiratory tube