Humans Argentina Ingeniería article human Adrenal Hyperplasia, Congenital Antropología Mutation Steroid 21-Hydroxylase congenital adrenal hyperplasia genetics steroid 21 monooxygenase CYP21A2 protein, human gene mutation genotype mutation priority journal Ciencias Naturales Mammalia Models, Molecular Protein Stability chemistry nucleotide sequence phenotype protein stability steroid 21 monooxygenase deficiency Algorithms Amino Acid Sequence Amyloid Binding Sites